Wounds are trauma induced defects of the human skin involving a multitude of endogenous
biochemical events and cellular reactions of the immune system. The healing process is …

The ability of vertebrates to regenerate amputated appendages is increasingly well-
understood at the cellular level. Cells mediating an innate immune response and …

Glucocorticoids (GCs), key mediators of stress signals, are also potent wound healing
inhibitors. To understand how stress signals inhibit wound healing, we investigated the role …

The back skin of C57 BL/6 mice was exposed to a single 400 mJ cm− 2 dose of ultraviolet B
(UVB), and parameters of hypothalamic–pituitary–adrenal (HPA) axis in relation to immune …

Purpose Hair cortisol evaluation has been used to help detect patients with suspected
Cushing syndrome. Our goal was to correlate segmental hair cortisol with biochemical …

Background: Recent studies have shown that production of cortisol not only takes place in
several non-adrenal peripheral tissues such as epithelial cells but, also, the local inter …

The factors involved in maintaining a localized inflammatory state in psoriatic skin remain
poorly understood. Here, we demonstrate through metabolomic and transcriptomic profiling …

Glucocorticoids (GC) are the primary steroids that regulate inflammation and have been
exploited therapeutically in inflammatory skin diseases. Despite the broad-spectrum …

The ex vivo human skin wound model is a widely accepted model to study wound
epithelialization. Due to a lack of animal models that fully replicate human conditions, the ex …

Scale removal in fish triggers a damage-repair program to re-establish the lost epidermis
and scale and an associated local immune response. In mammals, chronic stress is known …