Preeclampsia continues to afflict 5% to 8% of all pregnancies throughout the world and is
associated with significant morbidity and mortality to the mother and the fetus. Although the …

The release of extracellular vesicles (EV) by the syncytiotrophoblast (STB) may be an
important mechanism by which the placenta signals to the mother. STB derived EV (STBEV) …

Context There is a need to develop strategies for early prediction of patients who will
develop preeclampsia (PE) to establish preventive strategies to reduce the prevalence and …

Preeclampsia, a multisystem hypertensive disorder of pregnancy, is associated with
increased systemic vascular resistance. Placentae from patients with preeclampsia have …

Preeclampsia remains a leading cause of maternal and fetal mortality, due to ineffective
treatment and diagnostic strategies, compounded by the lack of clarity on the etiology of the …

The ability to directly monitor the status of the placenta throughout pregnancy would be a
major advance in both general and personalized obstetric care, allowing treatments to be …

Obesity is an important public health issue worldwide, where it is commonly associated with
the development of metabolic disorders, especially insulin resistance (IR). Maternal obesity …

The human placenta is a unique organ that performs the function of the majority of fetal
organs across gestation. How the placenta communicates with maternal tissues to prepare …

Endothelial cell markers are membrane-bound or cytoplasmic molecules expressed by
endothelial cells, which help their easier identification and discrimination from other cell …

The maternal physiology experiences numerous changes during pregnancy which are
essential in controlling and maintaining maternal metabolic adaptations and fetal …