[HTML][HTML] Addressing sufficiency of the CB1 receptor for endocannabinoid-mediated functions through conditional genetic rescue in forebrain GABAergic neurons

F Remmers, MD Lange, M Hamann, S Ruehle… - Brain Structure and …, 2017 - Springer
Genetic inactivation of the cannabinoid CB1 receptor gene in different cell types in the brain
has previously revealed necessary functions for distinct synaptic plasticity processes and …

Unravelling cortico-hypothalamic pathways regulating unconditioned fear-induced antinociception and defensive behaviours

LL Falconi-Sobrinho, T dos Anjos-Garcia… - …, 2017 - Elsevier
The medial prefrontal cortex can influence unconditioned fear-induced defensive
mechanisms organised by diencephalic neurons that are under tonic GABAergic inhibition …

Decrease in NMDA receptor-signalling activity in the anterior cingulate cortex diminishes defensive behaviour and unconditioned fear-induced antinociception elicited …

LL Falconi-Sobrinho, T dos Anjos-Garcia… - European …, 2017 - Elsevier
Acute γ-aminobutyric acid (GABA) disinhibition in the posterior hypothalamus (PH) elicits
defensive reactions that are considered anxiety-and panic attack-like behaviour, and these …

Panicolytic-like effects caused by substantia nigra pars reticulata pretreatment with low doses of endomorphin-1 and high doses of CTOP or the NOP receptors …

JA Da Silva, AF Biagioni, RC Almada, RL de Freitas… - …, 2017 - Springer
Rationale Gamma-aminobutyric acid (GABA) ergic neurons of the substantia nigra pars
reticulata (SNpr) are connected to the deep layers of the superior colliculus (dlSC). The …