The role of progesterone and the progesterone receptor in cancer

JH Check - Expert review of endocrinology & metabolism, 2017 - Taylor & Francis
Introduction: There is an abundance of accumulating data strongly suggesting there is a key
role for the progesterone receptor in the molecular events effecting the growth or …

Progesterone suppresses the invasion and migration of breast cancer cells irrespective of their progesterone receptor status-a short report

M Godbole, K Tiwary, R Badwe, S Gupta, A Dutt - Cellular oncology, 2017 - Springer
Purpose Pre-operative progesterone treatment of breast cancer has been shown to confer
survival benefits to patients independent of their progesterone receptor (PR) status. The …

Potential role of metronomic chemotherapy in the treatment of esophageal and gastroesophageal cancer

V Noronha, VM Patil, A Joshi, A Chougule, S Banavali… - Cancer Letters, 2017 - Elsevier
Patients with esophagogastric cancer have poor prognoses in spite of the best available
therapies. Patients are debilitated and may not tolerate, or may progress, on standard …

Repurposing non-cancer Drugs in Oncology–How many drugs are out there?

P Pantziarka, V Sukhatme, L Meheus, V Sukhatme… - bioRxiv, 2017 - biorxiv.org
Background Drug repurposing can speed up access to new therapeutic options for cancer
patients. With more than 2000 drugs approved worldwide and 6 relevant targets per drug on …

Perioperative therapies–Enhancing the impact of cancer surgery with repurposed drugs

P Pantziarka, G Bouche, R Sullivan, AM Ilbawi… - European Journal of …, 2017 - Elsevier
Surgical resection remains the major modality for modern curative treatment for solid
tumours. However, post-surgical recurrence, even following clear-margin resection and …

Surgical oophorectomy: a primary option in adjuvant treatment of premenopausal breast cancer

RR Love - Medical Research Archives, 2017 - esmed.org
Abstract Globally, there are 500,000 annual new cases of hormone-sensitive breast cancer
in premenopausal women; 400,000 of these occur in women in low and middle income …

A Review of Novel Approaches to Enhance Efficacy of Medical Treatment of Hormone Receptor Positive, Her2 Negative Breast Cancer

C Lee - 2017 - escholarship.org
The purpose of this project is to review approaches to improve the medical treatment of
breast cancer. This review will focus on the current literature that addresses (1) the current …