Antiallodynic effects of endomorphin-1 and endomorphin-2 in the spared nerve injury model of neuropathic pain in mice

C Wang, D Yang, B Yuan, T Qiu - Anesthesia & Analgesia, 2017 - journals.lww.com
BACKGROUND: The spared nerve injury (SNI) model is a new animal model that can mimic
several characteristics of clinical neuropathic pain. Opioids are recommended as treatment …

Original endomorphin-1 analogues exhibit good analgesic effects with minimal implications for human sperm motility

Y Wang, X Zhao, X Gao, Y Gan, Y Liu, X Zhao… - Bioorganic & Medicinal …, 2017 - Elsevier
To search a novel analgesic characterizes the effects on human sperm motility as minimal
as possible. A new class of endomorphin-1 (EM-1) analogues was synthesized by …

Original endomorphin-1 analogues exhibit good analgesic effects

Y Wu, X Zhao, Y Gan, X Zhang, H Wei, L Wang… - Bioorganic & Medicinal …, 2017 - Elsevier
A new class of endomorphin-1 analogues was synthesized by combining successful
chemical modifications including N-terminal guanidino modification, Phe 4 was chlorinated …

Distribution of endomorphin‐like‐immunoreactive neurones in the brain of the cichlid fish Oreochromis mossambicus

Vijayalaxmi, CB Ganesh - Journal of Neuroendocrinology, 2017 - Wiley Online Library
Endomorphins (EMs) are tetrapeptides involved in pain and neuroendocrine responses with
a high affinity for μ‐opioid receptors in mammals. In the present study, we investigated the …