Small-molecule targets in immuno-oncology

D Dhanak, JP Edwards, A Nguyen, PJ Tummino - Cell chemical biology, 2017 - cell.com
Advances in understanding the role and molecular mechanisms underlying immune
surveillance and control of (pre) malignancies is revolutionizing clinical practice in the …

Rise of PD‐L1 expression during metastasis of colorectal cancer: Implications for immunotherapy

HB Wang, H Yao, CS Li, LX Liang… - Journal of digestive …, 2017 - Wiley Online Library
OBJECTIVE Programmed death‐ligand 1 (PD‐L1) expression in colorectal cancer (CRC)
was implicated in predicting anti‐PD‐1/PD‐L1 therapy efficacy. However, therapeutic …

Integration of pharmacology, molecular pathology, and population data science to support precision gastrointestinal oncology

S Ogino, I Jhun, DA Mata, TR Soong, T Hamada… - NPJ precision …, 2017 - nature.com
Precision medicine has a goal of customizing disease prevention and treatment strategies.
Under the precision medicine paradigm, each patient has unique pathologic processes …

Génomique intégrée des neuroblastomes olfactifs: implications anatomopathologiques et thérapeutiques

M Classe - 2017 - theses.hal.science
Les neuroblastomes olfactifs (NBOs) sont des tumeurs rares de la base du crâne. Les outils
de classification de ces tumeurs sont insuffisants, il n'existe notamment aucune classification …