Factors affecting the FcRn-mediated transplacental transfer of antibodies and implications for vaccination in pregnancy

CR Wilcox, B Holder, CE Jones - Frontiers in immunology, 2017 - frontiersin.org
At birth, neonates are particularly vulnerable to infection and transplacental transfer of
immunoglobulin G (IgG) from mother to fetus provides crucial protection in the first weeks of …

Distribution of FcRn across species and tissues

S Latvala, B Jacobsen, MB Otteneder… - … of Histochemistry & …, 2017 - journals.sagepub.com
The neonatal Fc receptor (FcRn) is a major histocompatibility complex class I type molecule
that binds to, transports, and recycles immunoglobulin G (IgG) and albumin, thereby …

Allergen-specific IgG as a mediator of allergy inhibition: Lessons from mother to child

JR Victor - Human vaccines & immunotherapeutics, 2017 - Taylor & Francis
Allergen-specific IgG produced by immune mothers is associated with less predisposition to
allergy development in their children. This finding has been described by several groups …

Detailed characterization of monoclonal antibody receptor interaction using affinity liquid chromatography hyphenated to native mass spectrometry

R Gahoual, AK Heidenreich, GW Somsen… - Analytical …, 2017 - ACS Publications
We report on the online coupling of FcRn affinity liquid chromatography (LC) with
electrospray ionization mass spectrometry (ESI-MS) in native conditions to study the …

Vaccination of HIV-infected pregnant women: implications for protection of their young infants

Z Dangor, MC Nunes, G Kwatra, SG Lala… - Tropical Diseases, Travel …, 2017 - Springer
Background The prevention of mother to child transmission of HIV has resulted in reduced
burden of pediatric HIV-infection, but the prevalence of maternal HIV infection remains high …

HCV 母婴传播的分子机制及危险因素

高禄化, 聂青和 - 临床肝胆病杂志, 2017 - lcgdbzz.org
HCV 感染是一个全球性的健康问题, 人群普遍易感, 主要传播途径有血液传播, 性传播, 母婴传播.
血液制品抗HCV 筛查大大减少了HCV 血液传播几率. 直接抗病毒药物治疗丙型肝炎取得了突破 …

Protein Engineering: Methods and Applications

C Dobson, W Dall'Acqua - Protein Therapeutics, 2017 - Wiley Online Library
This chapter provides examples of different protein engineering techniques to elucidate
structure‐function relationships. These are illustrated with case studies describing the …

[图书][B] Fetal and neonatal alloimmune thrombocytopenia: immunological mechanisms and clinical consequences

E Refsum - 2017 - search.proquest.com
Fetal and neonatal alloimmune thrombocytopenia (FNAIT) is a rare condition that may
occurin connection with pregnancy, when maternal antibodies directed against paternally …

Перинатальні аспекти формування імунного статусу дитини

MV Makarenko, DA Govseev… - Перинатология и …, 2017 - pip.med-expert.com.ua
Аннотация Цель—обобщены литературные материалы за последние 30 лет о
современных представлениях относительно иммунологических аспектов в …

Research advances in molecular mechanism of mother-to-child transmission of HCV and related risk factors

G LuHua, N QingHe - 临床肝胆病杂志, 2017 - lcgdbzz.org
Hepatitis C virus (HCV) is a global health problem and people are generally susceptible to
HCV. Main routes of transmission include blood transmission, sexual transmission, and …