Biophysical stimuli presented to cells via microenvironmental properties (eg, alignment and
stiffness) or external forces have a significant impact on cell function and behavior. Recently …

Tissue engineering is a promising therapeutic strategy to regenerate skeletal muscle.
However, ex vivo cultivation methods typically result in a low differentiation efficiency of stem …

Local haemodynamics are linked to the non-uniform distribution of atherosclerosic lesions in
arteries. Low and oscillatory (reversing in the axial flow direction) wall shear stress (WSS) …

Computational modelling has received increasing attention to investigate multi-scale
coupled problems in micro-heterogeneous biological structures such as cells. In the current …

Tethering and rolling of circulating leukocytes on the surface of endothelium are critical
steps during an inflammatory response. A soft solid cell model was proposed to study …

This study was attempted to develop a new cell finite element model to present the cell
mechanical response underlying the compression. The geometry and material properties of …

Bone is an adaptive tissue that remodels in response to the mechanical loads placed upon it
during normal daily activity. This remodelling process is vital to maintaining the mechanical …