In vivo optophysiology reveals that G-protein activation triggers osmotic swelling and increased light scattering of rod photoreceptors

P Zhang, RJ Zawadzki, M Goswami… - Proceedings of the …, 2017 - National Acad Sciences
The light responses of rod and cone photoreceptors have been studied
electrophysiologically for decades, largely with ex vivo approaches that disrupt the …

Evolution of nonspectral rhodopsin function at high altitudes

GM Castiglione, FE Hauser, BS Liao… - Proceedings of the …, 2017 - National Acad Sciences
High-altitude environments present a range of biochemical and physiological challenges for
organisms through decreases in oxygen, pressure, and temperature relative to lowland …

[HTML][HTML] A simplified microwave-based motion detector for home cage activity monitoring in mice

A Genewsky, DE Heinz, PM Kaplick, K Kilonzo… - Journal of biological …, 2017 - Springer
Background Locomotor activity of rodents is an important readout to assess well-being and
physical health, and is pivotal for behavioral phenotyping. Measuring homecage-activity with …

[HTML][HTML] Spontaneous activation of visual pigments in relation to openness/closedness of chromophore-binding pocket

WWS Yue, R Frederiksen, X Ren, DG Luo, T Yamashita… - Elife, 2017 - elifesciences.org
Visual pigments can be spontaneously activated by internal thermal energy, generating
noise that interferes with real-light detection. Recently, we developed a physicochemical …

Heat shock antagonizes UVA-induced responses in murine melanocytes and melanoma cells: an unexpected interaction

LVM De Assis, MN Moraes… - Photochemical & …, 2017 - Springer
The skin is under the influence of oscillatory factors such as light and temperature. This
organ possesses a local system that controls several aspects in a time-dependent manner; …

Specific visible radiation facilitates lipolysis in mature 3T3-L1 adipocytes via rhodopsin-dependent β3-adrenergic signaling

PJ Park, JY Cho, EG Cho - European journal of cell biology, 2017 - Elsevier
The regulation of fat metabolism is important for maintaining functional and structural tissue
homeostasis in biological systems. Reducing excessive lipids has been an important …