Biological and clinical implications of comorbidities in Parkinson's disease
JA Santiago, V Bottero, JA Potashkin - Frontiers in aging …, 2017 - frontiersin.org
A wide spectrum of comorbidities has been associated with Parkinson's disease (PD), a
progressive neurodegenerative disease that affects more than seven million people …
progressive neurodegenerative disease that affects more than seven million people …
Premotor diagnosis of Parkinson's disease
H Reichmann - Neuroscience bulletin, 2017 - Springer
Typical Parkinsonian symptoms consist of bradykinesia plus rigidity and/or resting tremor.
Some time later postural instability occurs. Pre-motor symptoms such as hyposmia …
Some time later postural instability occurs. Pre-motor symptoms such as hyposmia …
A predictive model to identify Parkinson disease from administrative claims data
S Searles Nielsen, MN Warden, A Camacho-Soto… - Neurology, 2017 - AAN Enterprises
Objective: To use administrative medical claims data to identify patients with incident
Parkinson disease (PD) prior to diagnosis. Methods: Using a population-based case-control …
Parkinson disease (PD) prior to diagnosis. Methods: Using a population-based case-control …
Neuropsychiatric symptoms in untreated Parkinson's disease
S Szatmari, BMW Illigens, T Siepmann… - Neuropsychiatric …, 2017 - Taylor & Francis
Neuropsychiatric and cognitive symptoms are common in Parkinson's disease (PD) and may
precede and exceed motor symptoms as major factors impacting disease course and quality …
precede and exceed motor symptoms as major factors impacting disease course and quality …
Changes in neural circuitry associated with depression at pre-clinical, pre-motor and early motor phases of Parkinson's disease
J Borgonovo, C Allende-Castro, A Laliena… - Parkinsonism & Related …, 2017 - Elsevier
Abstract Although Parkinson's Disease (PD) is mostly considered a motor disorder, it can
present at early stages as a non-motor pathology. Among the non-motor clinical …
present at early stages as a non-motor pathology. Among the non-motor clinical …
Reconsidering the role of glial cells in chronic stress-induced dopaminergic neurons loss within the substantia nigra? Friend or foe?
LK Ong, Z Zhao, M Kluge, C TeBay, K Zalewska… - Brain, behavior, and …, 2017 - Elsevier
Exposure to psychological stress is known to seriously disrupt the operation of the
substantia nigra (SN) and may in fact initiate the loss of dopaminergic neurons within the …
substantia nigra (SN) and may in fact initiate the loss of dopaminergic neurons within the …
Physical comorbidity and its impact on symptom profile of depression among elderly patients attending psychiatry services of a tertiary care hospital
S Grover, E Dalla, A Mehra… - Indian Journal of …, 2017 - journals.sagepub.com
Aim: This study aimed to evaluate the prevalence of physical comorbidities among elderly
patients with depression attending psychiatric services and the secondary aim of the study …
patients with depression attending psychiatric services and the secondary aim of the study …
Prevalence of depressive symptoms and their association with brainstem raphe echogenicity in patients with Parkinson's disease and non-PD controls
Despite advances in diagnostics and clinical recognition, depressive symptoms in
Parkinson's disease (PD) exceeding normal limits remain effectively untreated. In this study …
Parkinson's disease (PD) exceeding normal limits remain effectively untreated. In this study …
Nonmotor symptoms in de novo Parkinson disease comparing to normal aging
PB Rožanković, M Rožanković, LV Novosel… - Clinical Neurology and …, 2017 - Elsevier
Abstract Objective Nonmotor symptoms (NMSs) are common in Parkinson disease (PD),
affecting patient's quality of life. The prevalence and domains of NMSs in untreated de novo …
affecting patient's quality of life. The prevalence and domains of NMSs in untreated de novo …
Treatment possibilities for psychosis in Parkinson's disease with an emphasis on the newly approved drug: Pimavanserin
Z Majlath, I Obal, L Vecsei - CNS & Neurological Disorders …, 2017 - ingentaconnect.com
Parkinson's disease (PD) is a progressive neurodegenerative disorder with prominent motor
and non-motor symptoms. Psychosis develops in over 40% of PD patients and it is one of …
and non-motor symptoms. Psychosis develops in over 40% of PD patients and it is one of …