Drug repurposing in cancer

L Sleire, HE Førde, IA Netland, L Leiss, BS Skeie… - Pharmacological …, 2017 - Elsevier
Cancer is a major health issue worldwide, and the global burden of cancer is expected to
increase in the coming years. Whereas the limited success with current therapies has driven …

Preventive therapy for cancer

J Cuzick - The lancet oncology, 2017 - thelancet.com
Therapeutic cancer prevention is a developing area that can gain a lot from the successes in
the prevention of cardiovascular diseases. Although weight control and physical activity are …

Федеральные клинические рекомендации по диагностике, лечению и профилактике остеопороза

ГА Мельниченко, ЖЕ Белая… - Проблемы …, 2017 - cyberleninka.ru
Скрининг для выявления групп с высокой вероятностью переломов рекомендован с
использованием алгоритма FRAX среди всех женщин в постменопаузе и мужчин …

Disease subtype–independent biomarkers of breast cancer chemoprevention by the ayurvedic medicine phytochemical withaferin A

SK Samanta, A Sehrawat, SH Kim… - JNCI: Journal of the …, 2017 - academic.oup.com
Background A nontoxic chemopreventive intervention efficacious against different subtypes
of breast cancer is still a clinically unmet need. The present study was undertaken to …

[HTML][HTML] Chemopreventive effects of atractylenolide II on mammary tumorigenesis via activating Nrf2-ARE pathway

T Wang, F Long, X Zhang, Y Yang, X Jiang, L Wang - Oncotarget, 2017 - ncbi.nlm.nih.gov
In the studies of chemoprevention, the Nrf2-ARE signaling pathway has received
widespread attention due to its anti-inflammatory and anti-oxidation effects. Our previous …

Preventing invasive breast cancer using endocrine therapy

MA Thorat, J Cuzick - The Breast, 2017 - Elsevier
Developments in breast cancer treatment have resulted in reduction in breast cancer
mortality in the developed world. However incidence continues to rise and greater use of …

Patient and medical barriers preclude uptake of tamoxifen preventative therapy in women with a strong family history

AR Skandarajah, S Thomas, K Shackleton… - The Breast, 2017 - Elsevier
Aims To assess the eligibility, uptake and impediments to tamoxifen use in high-risk women
attending a risk management clinic due to family history. Patients and methods All patients …

Постменопаузальный остеопороз: препараты кальция в современной стратегии профилактики и лечения

ЮЭ Доброхотова, МЗ Дугиева - РМЖ. Мать и дитя, 2017 - cyberleninka.ru
В лечении остеопороза за последние годы произошли существенные изменения,
связанные как с созданием нового класса высокоэффективных средств …

Pan Arab Osteoporosis Society guidelines for osteoporosis management

NA Jassim, G Adib, AAR Younis, FI Gorial… - Mediterranean …, 2017 - cyberleninka.ru
Osteoporosis is the most common bone disease in humans. With its related fragility fracture,
it represents a major public health problem in our region, with a significant medical and …

Skeletal fragility, a common menopausal burden: risk assessment, diagnosis, and management

MF Holick - Essentials of Menopause Management: A Case-Based …, 2017 - Springer
Osteoporosis and fracture are common in postmenopausal women. This chapter provides
review of the magnitude of the problem, risk factors, and causes for this insidious bone …