Amino-pyrimidine-containing spleen tyrosine kinase (Syk) inhibitors
MR Machacek - US Patent 9,624,210, 2017 - Google Patents
The invention provides certain amino-pyrimidine-contain ing compounds. The invention also
provides pharmaceutical compositions comprising such compounds, and methods of using …
provides pharmaceutical compositions comprising such compounds, and methods of using …
Thiazole-substituted aminoheteroaryls as spleen tyrosine kinase inhibitors
MR Machacek, ET Romeo, AB Northrup… - US Patent …, 2017 - Google Patents
The invention provides certain thiazole-substituted amino heteroaryl compounds of the
Formula (I) or pharmaceuti cally acceptable salts thereof, wherein R', R", RS, RC, A, Cy and …
Formula (I) or pharmaceuti cally acceptable salts thereof, wherein R', R", RS, RC, A, Cy and …
Thiazole-substituted aminoheteroaryls as spleen tyrosine kinase inhibitors
NJ Anthony, BM Andresen, AB Northrup… - US Patent …, 2017 - Google Patents
The invention provides certain thiazole-substituted amino heteroaryl compounds of the
Formula (I) or pharmaceuti cally acceptable salts thereof, wherein X, X2, X3, X4, Y', Y?, Y> …
Formula (I) or pharmaceuti cally acceptable salts thereof, wherein X, X2, X3, X4, Y', Y?, Y> …
Thiazole-substituted aminopyridines as spleen tyrosine kinase inhibitors
MD Altman, BM Andresen, KL Arrington… - US Patent …, 2017 - Google Patents
The invention provides certain thiazole-substituted amin opyridine compounds of the
Formula (I)(I) or pharmaceu tically acceptable salts thereof, wherein RRRRR RC, and the …
Formula (I)(I) or pharmaceu tically acceptable salts thereof, wherein RRRRR RC, and the …
Combination therapies
JL Kutok - 2017 - Google Patents
DEVSOMFAQLZNKR-RJRFIUFISA-N (Z)-3-[3-[3, 5-bis (trifluoromethyl) phenyl]-1, 2, 4-triazol-
1-yl]-N'-pyrazin-2-ylprop-2-enehydrazide Chemical group FC (F)(F) C1= CC (C (F)(F) F) …
1-yl]-N'-pyrazin-2-ylprop-2-enehydrazide Chemical group FC (F)(F) C1= CC (C (F)(F) F) …
2-pyrazine carboxamides as spleen tyrosine kinase inhibitors
MD Altman, B Cash, JM Ellis, ML Maddess… - US Patent …, 2017 - Google Patents
The invention provides certain pyrazine-2-carboxamide compounds of the Formula (I) or
pharmaceutically accept able salts thereof, wherein A, B, and X are as defined herein. The …
pharmaceutically accept able salts thereof, wherein A, B, and X are as defined herein. The …
Аминопиридинсодержащие ингибиторы тирозинкиназы селезенки (syk)
ЭТ РОМЕО, МР Машасек, БУ ТРОТТЕР… - RU Patent App …, 2017 - Google Patents
RU2612217C2 RU2013153540A RU2013153540A RU2612217C2 RU 2612217 C2
RU2612217 C2 RU 2612217C2 RU 2013153540 A RU2013153540 A RU 2013153540A …
RU2612217 C2 RU 2612217C2 RU 2013153540 A RU2013153540 A RU 2013153540A …
Thiazole-substituted aminoheteroaryls as spleen tyrosine kinase inhibitors
BM Andresen, KL Arrington, RD Otte, JM Ellis… - US Patent …, 2017 - Google Patents
WO 6, 911, 443 B2 6/2005 Yura et al. 7, 060, 827 B2 6/2006 Singh et al. 7, 122, 542 B2
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10/2006 Singh et al. 7, 803, 801 B2 9/2010 Kodama et al. 8, 551, 984 B2 10/2013 Altman et …
Thiazole-substituted aminoheteroaryls as Spleen Tyrosine Kinase inhibitors
TA Miller, A Petrocchi, ET Romeo, D Vitharana… - US Patent …, 2017 - Google Patents
US9670196B2 - Thiazole-substituted aminoheteroaryls as Spleen Tyrosine Kinase
inhibitors - Google Patents US9670196B2 - Thiazole-substituted aminoheteroaryls as …
inhibitors - Google Patents US9670196B2 - Thiazole-substituted aminoheteroaryls as …
Triazolyl derivatives as Syk inhibitors
MR Machacek, ET Romeo, SD Kattar… - US Patent …, 2017 - Google Patents
2016-01-20 Assigned to MERCK SHARP & DOHME CORP. reassignment MERCK SHARP
& DOHME CORP. ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR …
& DOHME CORP. ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR …