Background Millions of patients around the world are affected by neurological and
psychiatric disorders. Deep brain stimulation (DBS) is a device-based therapy that could …

The goal of this review is to describe in what ways feedback or adaptive stimulation may be
delivered and adjusted based on relevant biomarkers. Specific treatment mechanisms …

Brain stimulation is a promising therapy for several neurological disorders, including
Parkinson's disease. Stimulation parameters are selected empirically and are limited to the …

The goal of this study was to investigate subthalamic (STN) neural features of Freezers and
Non-Freezers with Parkinson's disease (PD), while freely walking without freezing of gait …

Deep brain stimulation (DBS) has compelling results in the desynchronization of the basal
ganglia neuronal activities and thus, is used in treating the motor symptoms of Parkinson's …

Abstract Systems and methods for stimulation of neurological tissue generate stimulation
trains with temporal patterns of stimulation, in which the interval between electrical pulses …

Background The motor thalamus is a key nodal point in the pallidothalamocortical “motor”
circuit, which has been implicated in the pathogenesis of Parkinson's disease (PD) and …

Deep brain stimulation (DBS) is a neurosurgical technique that consists of continuous
delivery of electrical pulses through chronically implanted electrodes connected to a …

Neuroprotection refers to the relative preservation of neuronal structure and function.
Neuroprotective agents refer to substances that are capable of preserving brain function and …

The purpose of this study was to test the feasibility of using a switched-capacitor discharge
stimulation (SCDS) system for electrical stimulation, and, subsequently, determine the …