[PDF][PDF] HPV16 E7 genetic conservation is critical to carcinogenesis

L Mirabello, M Yeager, K Yu, GM Clifford, Y Xiao, B Zhu… - Cell, 2017 - cell.com
Although most cervical human papillomavirus type 16 (HPV16) infections become
undetectable within 1–2 years, persistent HPV16 causes half of all cervical cancers. We …

Women's perspectives on human papillomavirus self‐sampling in the context of the UK cervical screening programme

D Williams, M Davies, A Fiander, D Farewell… - Health …, 2017 - Wiley Online Library
Background Testing for human papillomavirus (HPV) is being incorporated into the cervical
screening programme, with the probable future introduction of HPV as a primary test and a …

Risk stratification and long‐term risk prediction of E6 oncoprotein in a prospective screening cohort in C hina

Q Zhang, L Dong, S Hu, R Feng… - … journal of cancer, 2017 - Wiley Online Library
E6 oncoprotein is a necessary agent of HPV driven oncogenic transformation. This study is
aimed at evaluating the risk stratification potency of HPV 16/18 E6 oncoprotein (E6) as a …

Proof‐of‐principle study of a novel cervical screening and triage strategy: Computer‐analyzed cytology to decide which HPV‐positive women are likely to have≥ …

M Schiffman, K Yu, R Zuna… - … journal of cancer, 2017 - Wiley Online Library
A challenge in implementation of sensitive HPV‐based screening is limiting unnecessary
referrals to colposcopic biopsy. We combined two commonly recommended triage methods …

Different challenges in eliminating HPV16 compared to other types: a modeling study

I Baussano, F Lazzarato, G Ronco… - The Journal of …, 2017 - academic.oup.com
Background Human papillomavirus (HPV) vaccination is still not reaching many high-risk
populations. HPV16/18 vaccines offer cross-protection against other types, for example …

Prognostic value of human papillomavirus 16/18 genotyping in low-grade cervical lesions preceded by mildly abnormal cytology

J Ye, B Cheng, Y Cheng, Y Yao, X Xie, W Lu… - Journal of Zhejiang …, 2017 - Springer
Histological low-grade squamous intraepithelial lesion/cervical intraepithelial neoplasia
grade 1 (LSIL/CIN1) preceded by normal or mildly abnormal cytology is recommended for …

Intra‐ and inter‐observer reproducibility of CINtec® PLUS in ThinPrep® cytology preparations

M McMenamin, M McKenna, A McDowell… - …, 2017 - Wiley Online Library
Background This study evaluated the intra‐and inter‐observer reproducibility of the dual‐
stain biomarker, CIN tec® PLUS cytology in ThinPrep® specimens, for improved specificity …

[HTML][HTML] Human leukocyte antigen class I and class II polymorphisms and serum cytokine profiles in cervical cancer

L Bahls, R Yamakawa, K Zanão, D Alfieri… - International Journal of …, 2017 - mdpi.com
Only a small proportion of women who are exposed to infection with high-risk human
papillomavirus (HR-HPV) progress to persistent infection and develop cervical cancer (CC) …

[HTML][HTML] Persistence of type-specific human papillomavirus infection among Daqing City women in China with normal cytology: a pilot prospective study

N Li, D Hang, L Yang, X Feng, Z Lyu, S Xie, J Zhou… - Oncotarget, 2017 - ncbi.nlm.nih.gov
Persistence of high-risk human papillomavirus (HPV) represents the necessary cause of
cervical cancer. Researching natural history of HPV infection is important to identify high-risk …

Cervical cancer incidence after screening with HPV, cytology, and visual methods: 18‐Year follow‐up of the Guanacaste cohort

AC Rodríguez, C Ávila, R Herrero… - … journal of cancer, 2017 - Wiley Online Library
Testing negative for human papillomavirus (HPV) predicts long‐term reassurance against
invasive cervical cancer (ICC). To provide realistic estimates of effectiveness for new …