An extremely high dietary iodide supply forestalls severe hypothyroidism in Na+/I− symporter (NIS) knockout mice
G Ferrandino, RR Kaspari, A Reyna-Neyra… - Scientific reports, 2017 - nature.com
The sodium/iodide symporter (NIS) mediates active iodide (I−) accumulation in the thyroid,
the first step in thyroid hormone (TH) biosynthesis. Mutations in the SLC5A5 gene encoding …
the first step in thyroid hormone (TH) biosynthesis. Mutations in the SLC5A5 gene encoding …
Iodide binding in sodium-coupled cotransporters
Several apical iodide translocation pathways have been proposed for iodide efflux out of
thyroid follicular cells, including a pathway mediated by the sodium-coupled …
thyroid follicular cells, including a pathway mediated by the sodium-coupled …
The controversial role of pendrin in thyroid cell function and in the thyroid phenotype in Pendred syndrome
P Kopp, A Bizhanova, L Pesce - The Role of Pendrin in Health and …, 2017 - Springer
Thyroid hormones are essential for normal development, growth and differentiation of
numerous tissues, and metabolic regulation. Structurally, they are unique because they …
numerous tissues, and metabolic regulation. Structurally, they are unique because they …
Effect of curcumin on SMCT-1 expression and dichloroacetate toxicity in HCT116 colon cancer cells
T Intaraphairot, C Chinpaisal… - Pharmaceutical …, 2017 - library.go4manusub.com
Background: Colorectal cancer is a common cause of cancer-related deaths Epigenetic
regulation of the influx sodium dependent monocarboxylate transporter-1) SMCT1), a tumor …
regulation of the influx sodium dependent monocarboxylate transporter-1) SMCT1), a tumor …