Evidence for Health Decision Making — Beyond Randomized, Controlled Trials | New England
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Organisms have evolved to cope with geophysical cycles of different period lengths. In this
review, we focus on the adaptations of animals to the lunar cycle, specifically, on the …

The pathogenesis of left ventricular hypertrophy in patients with CKD is incompletely
understood. Sodium intake, which is usually assessed by measuring urinary sodium …

BACKGROUND. The idea that increasing salt intake increases drinking and urine volume is
widely accepted. We tested the hypothesis that an increase in salt intake of 6 g/d would …

Pathogenetic studies have demonstrated that the interdependency of sodium and potassium
affects blood pressure. Emerging evidences on the sodium-to-potassium ratio show benefits …

Background: A decrease in sodium intake has been shown to lower blood pressure, but data
from cohort studies on the association with cardiovascular and renal outcomes are …

Ingestion of sodium is essential to health, but excess sodium intake is a risk factor for
hypertension and cardiovascular disease. Defining an optimal range of sodium intake in …

Blood pressure salt sensitivity and salt resistance are mechanistically imperfectly explained.
A prescient systems medicine approach by Guyton and colleagues—more than 50 years …

The common notion is that the body Na+ is maintained within narrow limits for fluid and
blood pressure homeostasis. Several studies have, however, shown that considerable …

High dietary sodium intake triggers increased blood pressure (BP). Animal studies show that
dietary salt loading results in dermal Na+ accumulation and lymphangiogenesis mediated …