Abuse and misuse of pregabalin and gabapentin

KE Evoy, MD Morrison, SR Saklad - Drugs, 2017 - Springer
Background Gabapentinoid (pregabalin and gabapentin) abuse is increasingly being
reported. Objective To assess the extent of gabapentinoid abuse, characteristics of typical …

Prescription opioid abuse in chronic pain: an updated review of opioid abuse predictors and strategies to curb opioid abuse: part 1

AD Kaye, MR Jones, AM Kaye… - Pain …, 2017 - scholarlycommons.pacific.edu
Chronic pain and prescription opioid abuse are extremely prevalent both in this country and
worldwide. Consequences of opioid misuse can be life-threatening with significant morbidity …

Polysubstance use and misuse or abuse of prescription opioid analgesics: a multi-level analysis of international data

KI Morley, JA Ferris, AR Winstock, MT Lynskey - Pain, 2017 - journals.lww.com
Increasing mortality and morbidity associated with opioid analgesics has led to concerns
about their misuse and abuse, even when obtained through a prescription. These concerns …

A brief review of the genetics and pharmacogenetics of opioid use disorders

W Berrettini - Dialogues in clinical neuroscience, 2017 - Taylor & Francis
Increased physician prescribing of opioids to treat chronic nonprogressive pain has been
accompanied by an increase in opioid addiction. Twin studies of opioid addiction are …

[HTML][HTML] Using social listening data to monitor misuse and nonmedical use of bupropion: a content analysis

LS Anderson, HG Bell, M Gilbert… - JMIR Public Health …, 2017 - publichealth.jmir.org
Background: The nonmedical use of pharmaceutical products has become a significant
public health concern. Traditionally, the evaluation of nonmedical use has focused on …

A concept analysis of substance misuse to inform contemporary terminology

KF Mahmoud, D Finnell, CL Savage, KR Puskar… - Archives of psychiatric …, 2017 - Elsevier
Previous diagnostic categories of substance abuse and dependence have given way to the
current view that substance use disorders occur on a continuum with a broad range of …

Current and future development of extended-release, abuse-deterrent opioid formulations in the United States

LR Webster, J Markman, EJ Cone… - Postgraduate …, 2017 - Taylor & Francis
Prescription opioid misuse and abuse in the United States (US) is epidemic and is a major
burden on health-care resources and costs to society. The need to significantly reduce the …

Comparison of abuse, suspected suicidal intent, and fatalities related to the 7-day buprenorphine transdermal patch versus other opioid analgesics in the National …

PM Coplan, NE Sessler, V Harikrishnan… - Postgraduate …, 2017 - Taylor & Francis
Objective: Prescription opioid related abuse, suicide and death are significant public health
problems. This study compares rates of poison center calls categorized as intentional abuse …

Oral abuse potential, pharmacokinetics, and safety of once-daily, single-entity, extended-release hydrocodone (HYD) in recreational opioid users

SC Harris, A Cipriano, SV Colucci, RP Kapil… - Pain …, 2017 - academic.oup.com
Objectives. A once-daily, extended-release hydrocodone bitartrate tablet with abuse-
deterrent properties (Hysingla ER [HYD]) is available for the treatment of chronic pain in …

Prescription opioid abuse and misuse: Gap between primary-care investigator assessment and actual extent of these behaviors among patients with chronic pain

B Setnik, CL Roland, GC Pixton… - Postgraduate …, 2017 - Taylor & Francis
Objectives: To compare the results of two open-label primary care–based studies that
examined investigator assessment of patient risk for prescription opioid misuse, abuse, and …