Ironing out the cross talk between FGF23 and inflammation
The bone-secreted hormone fibroblast growth factor 23 (FGF23) has an essential role in
phosphate homeostasis by regulating expression of the kidney proximal tubule sodium …
phosphate homeostasis by regulating expression of the kidney proximal tubule sodium …
[HTML][HTML] Erythropoietin stimulates murine and human fibroblast growth factor-23, revealing novel roles for bone and bone marrow
EL Clinkenbeard, MR Hanudel, KR Stayrook… - …, 2017 - ncbi.nlm.nih.gov
Early stages of chronic kidney disease (CKD) are characterized by development of
progressive anemia1 as well as concurrent marked elevation of the phosphaturic hormone …
progressive anemia1 as well as concurrent marked elevation of the phosphaturic hormone …
Low serum iron is associated with high serum intact FGF23 in elderly men: the Swedish MrOS study
C Lewerin, Ö Ljunggren, H Nilsson-Ehle, MK Karlsson… - Bone, 2017 - Elsevier
Background Fibroblast growth factor (FGF23) is a protein that is produced by osteoblasts
and osteocytes. Increased serum levels of FGF23 have been associated with increased risks …
and osteocytes. Increased serum levels of FGF23 have been associated with increased risks …
Novel faces of fibroblast growth factor 23 (FGF23): iron deficiency, inflammation, insulin resistance, left ventricular hypertrophy, proteinuria and acute kidney injury
FGF23 is a hormone that appears as the core regulator of phosphate metabolism. Great deal
of data has accumulated to demonstrate increased FGF23 secretion from the bone to …
of data has accumulated to demonstrate increased FGF23 secretion from the bone to …
Fibroblast growth factor 23 actions in inflammation: a key factor in CKD outcomes
J Rossaint, M Unruh, A Zarbock - Nephrology Dialysis …, 2017 - academic.oup.com
During chronic kidney disease (CKD), bone mineral metabolism is disturbed owing in part to
the endogenous hormone fibroblast growth factor 23 (FGF23). Elevated FGF23 levels are …
the endogenous hormone fibroblast growth factor 23 (FGF23). Elevated FGF23 levels are …
Heritable and acquired disorders of phosphate metabolism: etiologies involving FGF23 and current therapeutics
EL Clinkenbeard, KE White - Bone, 2017 - Elsevier
Phosphate is critical for many cellular processes and structural functions, including as a key
molecule for nucleic acid synthesis and energy metabolism, as well as hydroxyapatite …
molecule for nucleic acid synthesis and energy metabolism, as well as hydroxyapatite …
[HTML][HTML] Carboxy-terminal fragment of fibroblast growth factor 23 induces heart hypertrophy in sickle cell disease
M Courbebaisse, H Mehel, C Petit-Hoang… - …, 2017 - ncbi.nlm.nih.gov
Our data are thus consistent with the release of cFGF23 in SCD patients. One study reported
an increase in iFGF23 plasma concentration in SCD children with elevated serum …
an increase in iFGF23 plasma concentration in SCD children with elevated serum …
Sex and iron modify fibroblast growth factor 23 concentration in 1-year-old children
E Holmlund-Suila, M Enlund-Cerullo… - The Journal of …, 2017 - academic.oup.com
Context Fibroblast growth factor 23 (FGF23) plays an important role in phosphate
homeostasis, but its regulation is inadequately characterized. Objective To examine FGF23 …
homeostasis, but its regulation is inadequately characterized. Objective To examine FGF23 …
[HTML][HTML] The metabolic bone disease associated with the Hyp mutation is independent of osteoblastic HIF1α expression
Abstract Fibroblast growth factor-23 (FGF23) controls key responses to systemic phosphate
increases through its phosphaturic actions on the kidney. In addition to stimulation by …
increases through its phosphaturic actions on the kidney. In addition to stimulation by …