Medications development for the treatment of alcohol use disorder: insights into the predictive value of animal and human laboratory models
MM Yardley, LA Ray - Addiction biology, 2017 - Wiley Online Library
Abstract Development of effective treatments for alcohol use disorder (AUD) represents an
important public health goal. This review provides a summary of completed preclinical and …
important public health goal. This review provides a summary of completed preclinical and …
Daily home fortification with iron as ferrous fumarate versus NaFeEDTA: a randomised, placebo-controlled, non-inferiority trial in Kenyan children
EM Teshome, PEA Andang'o, V Osoti, SR Terwel… - BMC medicine, 2017 - Springer
Background We aimed to show the non-inferiority of home fortification with a daily dose of 3
mg iron in the form of iron as ferric sodium ethylenediaminetetraacetate (NaFeEDTA) …
mg iron in the form of iron as ferric sodium ethylenediaminetetraacetate (NaFeEDTA) …
A studentized permutation test for three‐arm trials in the 'gold standard'design
T Mütze, F Konietschke, A Munk… - Statistics in Medicine, 2017 - Wiley Online Library
The 'gold standard'design for three‐arm trials refers to trials with an active control and a
placebo control in addition to the experimental treatment group. This trial design is …
placebo control in addition to the experimental treatment group. This trial design is …
The ethics of clinical trials research in severe mood disorders
Mood disorders, including major depressive disorder (MDD) and bipolar disorder (BD), are
highly prevalent, frequently disabling, and sometimes deadly. Additional research and more …
highly prevalent, frequently disabling, and sometimes deadly. Additional research and more …
[HTML][HTML] Comparison of home fortification with two iron formulations among Kenyan children: Rationale and design of a placebo-controlled non-inferiority trial
EM Teshome, W Otieno, SR Terwel, V Osoti… - Contemporary clinical …, 2017 - Elsevier
Introduction Home fortification powders containing iron and other micronutrients have been
recommended by World Health Organisation to prevent iron deficiency anaemia in areas of …
recommended by World Health Organisation to prevent iron deficiency anaemia in areas of …
A pilot randomised controlled trial comparing antipsychotic medication, to cognitive behavioural therapy to a combination of both in people with psychosis: rationale …
Aims: Ongoing NICE guidance recommends research on the clinical and cost effectiveness
of psychological treatment alone, compared to antipsychotic medication and compared to …
of psychological treatment alone, compared to antipsychotic medication and compared to …
Drug versus placebo randomized controlled trials in neonates: A review of ClinicalTrials. gov registry
E Desselas, C Pansieri, S Leroux, M Bonati… - Plos one, 2017 - journals.plos.org
Background Despite specific initiatives and identified needs, most neonatal drugs are still
used off-label, with variable dosage administrations and schedules. In high risk preterm and …
used off-label, with variable dosage administrations and schedules. In high risk preterm and …
[图书][B] Informed choice of medical services: is the law just?
M Milburn - 2017 - taylorfrancis.com
This title was first published in 2001. This work is a uniquely multi-disciplinary contribution to
the existing bioethical literature on the topic of informed choice of medical services. It is also …
the existing bioethical literature on the topic of informed choice of medical services. It is also …
A placebo alkalmazásának etikai vonatkozásai
V Bodnár, G Bárdos - Magyar Pszichológiai Szemle, 2017 - akjournals.com
Jelen tanulmány a placebo terápiás és klinikai kutatásokban történő felhasználásának etikai
kérdéseit veszi sorra, külön hangsúlyt helyezve a megtévesztés, az egészségügyi hátrány, a …
kérdéseit veszi sorra, külön hangsúlyt helyezve a megtévesztés, az egészségügyi hátrány, a …
Regulating research for the decisionally impaired: implications for mental health professionals
MB Kapp - Human Experimentation and Research, 2017 - taylorfrancis.com
Mental health professionals, in fulfilling their different roles, often become involved with
research protocols involving decisionally impaired current or prospective human subjects …
research protocols involving decisionally impaired current or prospective human subjects …