[HTML][HTML] Circular RNAs: biogenesis, function and role in human diseases

J Greene, AM Baird, L Brady, M Lim… - Frontiers in molecular …, 2017 - frontiersin.org
Circular RNAs (circRNAs) are currently classed as non-coding RNA (ncRNA) that, unlike
linear RNAs, form covalently closed continuous loops and act as gene regulators in …

Regulatory effects of berberine on microRNome in cancer and other conditions

SH Ayati, B Fazeli, AA Momtazi-Borojeni… - Critical reviews in …, 2017 - Elsevier
Berberine (BBR) is an isoquinoline alkaloid found in different plant families such as
Berberidaceae, Ranunculaceae, and Papaveraceae. BBR is well-known for its anti …

[HTML][HTML] miR-378 suppresses the proliferation, migration and invasion of colon cancer cells by inhibiting SDAD1

M Zeng, L Zhu, L Li, C Kang - Cellular & Molecular Biology Letters, 2017 - Springer
Background MicroRNAs (miRNAs) play important roles in the growth and metastasis of
colon cancer. It is known that one set of miRNAs are dysregulated in colon cancer cells, but …

Chemosensitization and inhibition of pancreatic cancer stem cell proliferation by overexpression of microRNA-205

AK Chaudhary, G Mondal, V Kumar, K Kattel… - Cancer letters, 2017 - Elsevier
Abstract Treatment of pancreatic cancer with gemcitabine (GEM) is limited due to its rapid
plasma metabolism and development of chemoresistance. MicroRNA (miRNA) regulates …

The co‐regulatory networks of tumor suppressor genes, oncogenes, and miRNAs in colorectal cancer

ML Slattery, JS Herrick, LE Mullany… - Genes …, 2017 - Wiley Online Library
Tumor suppressor genes (TSGs) and oncogenes (OG) are involved in carcinogenesis.
MiRNAs also contribute to cellular pathways leading to cancer. We use data from 217 …

[HTML][HTML] Decreased expression of miR-939 contributes to chemoresistance and metastasis of gastric cancer via dysregulation of SLC34A2 and Raf/MEK/ERK pathway

JX Zhang, Y Xu, Y Gao, C Chen, ZS Zheng, M Yun… - Molecular cancer, 2017 - Springer
Background The development of chemoresistance and metastasis are the leading causes of
death for gastric cancer (GC) patients, however, the molecular mechanisms involved remain …

[HTML][HTML] MicroRNA-29c functions as a tumor suppressor by targeting VEGFA in lung adenocarcinoma

L Liu, N Bi, L Wu, X Ding, Y Men, W Zhou, L Li… - Molecular cancer, 2017 - Springer
Background Lung adenocarcinoma (LAD) is considered to be a highly aggressive disease
with heterogeneous prognosis and the molecular mechanisms underlying tumor …

[HTML][HTML] Molecular mechanisms and pathways as targets for cancer prevention and progression with dietary compounds

N Nosrati, M Bakovic, G Paliyath - International journal of molecular …, 2017 - mdpi.com
A unique feature of bioactive food ingredients is their broad antioxidant function.
Antioxidants having a wide spectrum of chemical structure and activity beyond basic …

MiR-93-5p inhibits the EMT of breast cancer cells via targeting MKL-1 and STAT3

Y Xiang, XH Liao, CX Yu, A Yao, H Qin, JP Li… - Experimental cell …, 2017 - Elsevier
Epithelial-mesenchymal transition (EMT) plays an important role in breast cancer cell
metastasis. Both (megakaryoblastic leukemia)/myocardin-like 1 (MKL-1) and Signal …

[HTML][HTML] Genetic variation and RNA structure regulate microRNA biogenesis

N Fernandez, RA Cordiner, RS Young, N Hug… - Nature …, 2017 - nature.com
MiRNA biogenesis is highly regulated at the post-transcriptional level; however, the role of
sequence and secondary RNA structure in this process has not been extensively studied. A …