A systematic review and integrative approach to decode the common molecular link between levodopa response and Parkinson's disease
Background PD is a progressive neurodegenerative disorder commonly treated by
levodopa. The findings from genetic studies on adverse effects (ADRs) and levodopa …
levodopa. The findings from genetic studies on adverse effects (ADRs) and levodopa …
Pharmacogenetics of Parkinson's disease in clinical practice
Background Pharmacogenetics aims to identify the genetic factors participating in the
heterogeneity of drug response. The ultimate goal is to provide personalized treatment by …
heterogeneity of drug response. The ultimate goal is to provide personalized treatment by …
Roles of functional catechol-O-methyltransferase genotypes in Chinese patients with Parkinson's disease
Y Qian, J Liu, S Xu, X Yang, Q Xiao - Translational Neurodegeneration, 2017 - Springer
Background Recent studies have found that the functional catechol-O-methyltransferase
(COMT) gene may be associated with the susceptibility to and pharmacotherapy of …
(COMT) gene may be associated with the susceptibility to and pharmacotherapy of …