Acquired hemophilia A: updated review of evidence and treatment guidance

R Kruse‐Jarres, CL Kempton, F Baudo… - American journal of …, 2017 - Wiley Online Library
Acquired hemophilia A (AHA) is a rare disease resulting from autoantibodies (inhibitors)
against endogenous factor VIII (FVIII) that leads to bleeding, which is often spontaneous and …

Acquired hemophilia A: a review of recent data and new therapeutic options

M Franchini, S Vaglio, G Marano, C Mengoli… - …, 2017 - Taylor & Francis
ABSTRACT Objectives: Acquired hemophilia A (AHA) is a rare, but potentially life-
threatening, bleeding disorder caused by an autoantibody against factor VIII that interferes …

Recombinant porcine sequence factor VIII (rp FVIII) for acquired haemophilia A: practical clinical experience of its use in seven patients

MD Tarantino, A Cuker, B Hardesty, JC Roberts… - …, 2017 - Wiley Online Library
Introduction A recombinant porcine factor VIII B‐domain‐deleted product (rp FVIII; OBIZUR,
Baxalta Incorporated, Deerfield, IL 60015, USA) was recently approved for treatment of …

Clot waveform analysis using CS‐2000i™ distinguishes between very low and absent levels of factor VIII activity in patients with severe haemophilia A

T Matsumoto, K Nogami, Y Tabuchi, K Yada… - …, 2017 - Wiley Online Library
Introduction A recently developed method to assess comprehensive coagulation function,
clot waveform analysis (CWA), accurately detect low levels (< 1 IU/dL) of factor VIII activity …

Successful management of acquired hemophilia a associated with bullous pemphigoid: a case report and review of the literature

Q Binet, C Lambert, L Sacré… - Case Reports in …, 2017 - Wiley Online Library
Background. Acquired hemophilia A (AHA) is a rare condition, due to the spontaneous
formation of neutralizing antibodies against endogenous factor VIII. About half the cases are …

Review of recombinant anti-haemophilic porcine sequence factor VIII in adults with acquired haemophilia A

E Fosbury, A Drebes, A Riddell… - Therapeutic Advances …, 2017 - journals.sagepub.com
Acquired haemophilia A (AHA) is a rare, serious bleeding disorder most often encountered
in elderly patients. The mainstay of haemostatic management is with bypassing agents …

Treatment of acute bleeding in acquired haemophilia A with recombinant activated factor VII: analysis of 10‐year Japanese postmarketing surveillance data

K Amano, I Seita, S Higasa, A Sawada… - …, 2017 - Wiley Online Library
Introduction Patients with acquired haemophilia A (AHA) have autoantibodies against factor
VIII (FVIII), and may develop spontaneous bleeding that requires treatment with FVIII …

Possible assessment of coagulation function and haemostasis therapy using comprehensive coagulation assays in a patient with acquired haemophilia A.

M Takeyama, K Nogami, T Matsumoto… - …, 2017 - search.ebscohost.com
The article focuses on the study related to the treatment of an autoimmune disorder acquired
by haemophilia A (AHA) which is caused by the development of blood coagulation factor VIII …

Rare bleeding disorders-old diseases in the era of novel options for therapy

T Livnat, AA Barg, S Levy-Mendelovich… - Blood Cells, Molecules …, 2017 - Elsevier
Rare diseases are defined as life-threatening or chronically debilitating diseases with a
prevalence of less than one per 2000 according to the European Union or one per 1250 …

An extra X does not prevent acquired hemophilia–Pregnancy-associated acquired hemophilia A

AA Barg, T Livnat, G Kenet - Thrombosis Research, 2017 - Elsevier
Acquired hemophilia A (AHA) is a severe bleeding disorder caused by autoantibodies
against clotting factor VIII (FVIII). With an estimated annual incidence of 1.3 to 1.5 per million …