Protein–RNA docking is still an open question. One of the main challenges is to develop an
effective scoring function that can discriminate near‐native structures from the incorrect …

Deciphering the structural and energetic determinants of protein-RNA interactions harbors
the potential to understand key cell processes at molecular level, such as gene expression …

Computational prediction of RNA-protein complex 3D structures includes two basic steps:
one is sampling possible structures and another is scoring the sampled structures to pick out …

FOXP2 is a member of the P subfamily of FOX transcription factors, the DNA-binding domain
of which is the winged helix forkhead domain (FHD). In this work we show that the FOXP2 …

Die Aufrechterhaltung des Stoffwechsels und der Funktion von lebenden Zellen erfordert
das Zusammenspiel komplexer Proteinnetzwerke. Diese ermöglichen der Zelle, variierende …

Abstract [eng] This dissertation describes three novel effective methods for the analysis and
evaluation of biomolecular structures. The presented methods construct and utilize the …