Carbon dots: biomacromolecule interaction, bioimaging and nanomedicine
Carbon dots, a recent member of the renowned carbon-based nanomaterials family, have
attracted significant interest from various fields. The extraordinary properties, including …
attracted significant interest from various fields. The extraordinary properties, including …
Peptide-based strategies for enhanced cell uptake, transcellular transport, and circulation: Mechanisms and challenges
Peptides are emerging as a new tool in drug and gene delivery. Peptide-drug conjugates
and peptide-modified drug delivery systems provide new opportunities to avoid macrophage …
and peptide-modified drug delivery systems provide new opportunities to avoid macrophage …
Dual-modified liposome codelivery of doxorubicin and vincristine improve targeting and therapeutic efficacy of glioma
Y Zhang, M Zhai, Z Chen, X Han, F Yu, Z Li, X Xie… - Drug …, 2017 - Taylor & Francis
Therapeutic outcome for the treatment of glioma was often limited due to drug resistance
and low permeability of drug across the multiple physiological barriers, including the blood …
and low permeability of drug across the multiple physiological barriers, including the blood …
On-demand drug release from dual-targeting small nanoparticles triggered by high-intensity focused ultrasound enhanced glioblastoma-targeting therapy
Glioblastoma is one of the most challenging and intractable tumors with the difficult
treatment and poor prognosis. Unsatisfactory traditional systemic chemotherapies for …
treatment and poor prognosis. Unsatisfactory traditional systemic chemotherapies for …
Blood-brain barrier-penetrating amphiphilic polymer nanoparticles deliver docetaxel for the treatment of brain metastases of triple negative breast cancer
Brain metastasis is a fatal disease with limited treatment options and very short survival.
Although systemic chemotherapy has some effect on peripheral metastases of breast …
Although systemic chemotherapy has some effect on peripheral metastases of breast …
Perspectives on dual targeting delivery systems for brain tumors
H Gao - Journal of Neuroimmune Pharmacology, 2017 - Springer
Brain tumor remains one of the most serious threats to human beings. Different from
peripheral tumors, drug delivery to brain tumor is largely restricted by the blood brain barrier …
peripheral tumors, drug delivery to brain tumor is largely restricted by the blood brain barrier …
Noninvasive nanoparticle strategies for brain tumor targeting
The blood–brain barrier (BBB) maintains the integrity and homeostasis of the central
nervous system (CNS) yet represents an intimidating hurdle for efficient drug delivery to …
nervous system (CNS) yet represents an intimidating hurdle for efficient drug delivery to …
Challenges and recent advances in medulloblastoma therapy
Medulloblastoma (MB) is the most common childhood brain tumor, which occurs in the
posterior fossa. MB tumors are highly heterogeneous and have diverse genetic make-ups …
posterior fossa. MB tumors are highly heterogeneous and have diverse genetic make-ups …
Blood–brain barrier peptide shuttles
M Sánchez-Navarro, E Giralt, M Teixidó - Current opinion in chemical …, 2017 - Elsevier
Highlights•Targeting of the BBB is a great opportunity for brain delivery of therapeutics.•BBB
peptide shuttles can target both passive and active transport mechanisms present at the …
peptide shuttles can target both passive and active transport mechanisms present at the …
A facile way of modifying layered double hydroxide nanoparticles with targeting ligand-conjugated albumin for enhanced delivery to brain tumour cells
Active targeting of nanoparticles (NPs) for cancer treatment has attracted increasing interest
in the past decades. Various ligand modification strategies have been used to enhance the …
in the past decades. Various ligand modification strategies have been used to enhance the …