Low intensity, non-noxious, stimulation of cutaneous somatosensory nerves has been
shown to trigger oxytocin release and is associated with increased social motivation, plus …

The sensation of touch is mediated by mechanosensory neurons that are embedded in skin
and relay signals from the periphery to the central nervous system. During embryogenesis …

The deep dorsal horn is a poorly characterized spinal cord region implicated in processing
low-threshold mechanoreceptor (LTMR) information. We report an array of mouse genetic …

The trigeminal ganglion contains somatosensory neurons that detect a range of thermal,
mechanical and chemical cues and innervate unique sensory compartments in the head …

Painful mechanical stimuli activate multiple peripheral sensory afferent subtypes
simultaneously, including nociceptors and low-threshold mechanoreceptors (LTMRs). Using …

Diabetic patients frequently suffer from continuous pain that is poorly treated by currently
available analgesics. We used mouse models of type 1 and type 2 diabetes to investigate a …

The somatosensory system provides animals with the ability to detect, distinguish, and
respond to diverse thermal, mechanical, and irritating stimuli. While there has been progress …

Background C‐tactile (CT) afferents are unmyelinated low‐threshold mechanoreceptors
optimized for signalling affective, gentle touch. In three separate psychophysical …

Insects and mammals share similarities of neural organization underlying the perception of
odors, taste, vision, sound, and gravity. We observed that insect somatosensation also …

Osteopathic medicine is a system of manual diagnosis and treatment. While there is growing
evidence that osteopathy is effective in a range of clinical conditions, the underlying …