[HTML][HTML] Drug targeting to myofibroblasts: Implications for fibrosis and cancer

S Yazdani, R Bansal, J Prakash - Advanced drug delivery reviews, 2017 - Elsevier
Myofibroblasts are the key players in extracellular matrix remodeling, a core phenomenon in
numerous devastating fibrotic diseases. Not only in organ fibrosis, but also the pivotal role of …

RGD-modified albumin nanoconjugates for targeted delivery of a porphyrin photosensitizer

F Li, Y Zhao, C Mao, Y Kong, X Ming - Molecular pharmaceutics, 2017 - ACS Publications
Advances in photodynamic therapy of cancer have been restrained by lack of cancer
specificity and side effects to normal tissues. Molecularly targeted photodynamic therapy can …

Development of liver cell-targeted drug delivery systems: experimental approaches

YA Ivanenkov, SY Maklakova… - Russian Chemical …, 2017 - iopscience.iop.org
The review is devoted to liver cell-targeted drug delivery systems. Primary attention is paid to
the therapy of hepatocellular carcinoma, liver fibrosis, liver cirrhosis, viral hepatitis (A–G) …

[HTML][HTML] Discovery of aptamer ligands for hepatic stellate cells using SELEX

Z Chen, H Liu, A Jain, L Zhang, C Liu, K Cheng - Theranostics, 2017 - ncbi.nlm.nih.gov
Insulin like growth factor II receptor (IGFIIR) is a transmembrane protein overexpressed in
activated hepatic stellate cells (HSCs), which are the major target for the treatment of liver …

[HTML][HTML] Polymeric microspheres for the sustained release of a protein-based drug carrier targeting the PDGFβ-receptor in the fibrotic kidney

N Teekamp, F Van Dijk, A Broesder, M Evers… - International Journal of …, 2017 - Elsevier
Injectable sustained release drug delivery systems are an attractive alternative for the
intravenous delivery of therapeutic proteins. In particular, for chronic diseases such as …

[PDF][PDF] Экспериментальные направления в разработке средств направленной доставки лекарственных препаратов в клетки печени

ЯА Иваненков, СЮ Маклакова, ЕК Белоглазкина… - Успехи химии, 2017 - uspkhim.ru
В начале XX в. Пауль Эрлих сформулировал фундаментальную концепцию «magic
bullet» ì нацеленного (или направленного, адресного) транспорта молекул …