Antibiotic resistance can be acquired by mutation or horizontal transfer of a resistance gene,
and generally an acquired mechanism results in a predictable increase in phenotypic …

Ever since antibiotics were introduced into human and veterinary medicine to treat and
prevent bacterial infections there has been a steady selection and increase in the frequency …

Pseudomonas aeruginosa is an important opportunistic human pathogen that lives in biofilm-
like cell aggregates at sites of chronic infection, such as those that occur in the lungs of …

To characterise Pseudomonas aeruginosa populations during chronic lung infections of non-
cystic fibrosis bronchiectasis patients, we used whole-genome sequencing to 1) assess the …

As antimicrobial-resistant microbes become increasingly common and a significant global
issue, novel approaches to treating these infections particularly in those at high risk are …

Background Pseudomonas aeruginosa typically displays loss of virulence-associated
secretions over the course of chronic cystic fibrosis infections. This has led to the suggestion …

Pseudomonas aeruginosa (PA), a nonlactose fermenting gram-negative bacillus, is a
common cause of nosocomial infections in critically ill or debilitated patients, particularly …

A Pseudomonas aeruginosa AUST-02 strain sub-type (M3L7) has been identified in
Australia, infects the lungs of some people with cystic fibrosis and is associated with …

Rationale Epidemic Pseudomonas aeruginosa (PA) plays an important role in cystic fibrosis
(CF) lung disease. A novel strain, the 'Prairie Epidemic Strain'(PES), has been identified in …

The first Spanish multi-centre study on the microbiology of cystic fibrosis (CF) was conducted
from 2013 to 2014. The study involved 24 CF units from 17 hospitals, and recruited 341 …