Acute respiratory distress syndrome (ARDS) is defined as a syndrome of acute onset, with
bilateral opacities on chest imaging and respiratory failure not caused by cardiac failure …

A growing literature indicates that mitochondria are key participants in innate immune
pathways, functioning as both signaling platforms and contributing to effector responses. In …

The generation of reactive oxygen species (ROS) plays an important role for the
maintenance of cellular processes and functions in the body. However, the excessive …

Remarkable new roles for mitochondria in calcium handling, apoptosis, heme turnover,
inflammation, and oxygen and nutrient sensing have been discovered for organelles that …

BACKGROUND Massive transfusions are accompanied by an increased incidence of a
particularly aggressive and lethal form of acute lung injury (delayed transfusion-related …

Mitochondria are key organelles involved in energy production, functioning as the metabolic
hubs of cells. Recent findings emphasize the emerging role of the mitochondrion as a key …

The pathogenesis of preeclampsia remains unclear but placental factors are known to play a
crucial role causing maternal endothelial cell dysfunction. One potential factor is placental …

Satisfactory therapeutic strategies for septic shock are still missing. Previously we found
elevated levels of Wnt5A in patients with severe sepsis and septic shock. Wnt5A is released …

Background Cell free deoxyribonucleic acid (cfDNA) has been proposed as a biomarker of
secondary complications following trauma. Raised thrombomodulin and syndecan-1 levels …

Background: The purpose of our study was to determine prospectively relationships
between plasma mitochondrial deoxyribonucleic acid (mtDNA) concentration and clinical …