Abstract Nigella sativa (N. sativa), which belongs to the botanical family of Ranunculaceae,
is a widely used medicinal plant all over the world. N. sativa seeds and oil have been used …

Three-dimensional cell culture is emerging as a more relevant alternative to the traditional
two-dimensional format. Yet the ability to perform cytometry at the single cell level on intact …

The liver, a main detoxification organ, has evolved a complex enzymatic system to respond
to multiple pathological conditions, in which leucine aminopeptidase (LAP) has been …

Oxidative stress has a critical role in the pathogenesis of acetaminophen (APAP) induced
hepatocellular necrosis, and the identification of novel approaches to attenuate oxidative …

To examine the effects of formononetin (FMN) on Acetaminophen (APAP)-induced liver
injury in vitro and in vivo. Human non-tumor hepatic cells LO2 were pretreated with either …

Increasing evidence indicates that interleukin-22 (IL-22) holds tremendous potential as a
protective agent in preventing liver injury, but its pleiotropic effects and pathogenic role in …

Saikosaponin a (SSa) is one of the main active components of Bupleurum falcatum. It is
commonly used to treat liver injury and fibrosis in traditional Chinese medicine. Our previous …

Background The present study investigated the potential of methanolic extract of
Dicranopteris linearis (MEDL) leaves to attenuate liver intoxication induced by …

Human pharmaceuticals such as Acetaminophen, Atenolol and Carbamazepine are pseudo
persistent aquatic pollutants with yet unknown sub-lethal effects at environmentally relevant …

Acute liver failure (ALF) is a dramatic life‐threatening illness defined by the sudden onset of
coagulopathy and hepatic encephalopathy in an individual without preexisting liver disease …