Salvia miltiorrhiza Bunge (Danshen) extract attenuates permanent cerebral ischemia through inhibiting platelet activation in rats

Y Fei, S Wang, L Yang, Y Qiu, Y Li, W Liu, T Xi… - Journal of …, 2017 - Elsevier
Ethnopharmacological relevance Danshen is a crude herbal drug isolated from dried roots
of Salvia miltiorrhiza Bunge. This plant is widely used in oriental medicine for the treatment …

Neuroprotective effect of lercanidipine in middle cerebral artery occlusion model of stroke in rats

S Gupta, U Sharma, NR Jagannathan, YK Gupta - Experimental neurology, 2017 - Elsevier
Oxidative stress, inflammation and apoptotic neuronal cell death are cardinal mechanisms
involved in the cascade of acute ischemic stroke. Lercanidipine apart from calcium channel …

Monitoring acute stroke in mouse model using laser speckle imaging-guided visible-light optical coherence tomography

Q Liu, S Chen, B Soetikno, W Liu… - IEEE Transactions on …, 2017 - ieeexplore.ieee.org
Objective: Monitoring hemodynamic and vascular changes in the acute stages of mouse
stroke models is invaluable in studying ischemic stroke pathophysiology. However, there …

[HTML][HTML] High-density speckle contrast optical tomography (SCOT) for three dimensional tomographic imaging of the small animal brain

T Dragojević, HM Varma, JL Hollmann, CP Valdes… - NeuroImage, 2017 - Elsevier
High-density speckle contrast optical tomography (SCOT) utilizing tens of thousands of
source-detector pairs, was developed for in vivo imaging of blood flow in small animals. The …

Alterations in neurovascular coupling following acute traumatic brain injury

H Jang, S Huang, DX Hammer, L Wang… - …, 2017 - spiedigitallibrary.org
Following acute traumatic brain injury (TBI), timely transport to a hospital can significantly
improve the prognosis for recovery. There is, however, a dearth of quantitative biomarkers …

[HTML][HTML] Redistribution of cerebral blood flow during severe hypovolemia and reperfusion in a sheep model: Critical role of α1-adrenergic signaling

R Schiffner, SJ Bischoff, T Lehmann, F Rakers… - International journal of …, 2017 - mdpi.com
Background: Maintenance of brain circulation during shock is sufficient to prevent
subcortical injury but the cerebral cortex is not spared. This suggests area-specific …

[PDF][PDF] Changes of cortical perfusion in the early phase of subarachnoid bleeding in a rat model and the role of intracranial hypertension

M Kolar, K Nohejlova, F Duska, J Mares… - Physiol Res, 2017 - pdfs.semanticscholar.org
Changes of Cortical Perfusion in the Early Phase of Subarachnoid Bleeding in a Rat Model
and the Role of Intracranial Hypertensi Page 1 PHYSIOLOGICAL RESEARCH • ISSN 0862-8408(print) …

Longitudinal, transcranial measurement of functional activation in the rat brain by diffuse correlation spectroscopy

I Blanco, P Zirak, T Dragojević, C Castellvi… - …, 2017 - spiedigitallibrary.org
Neural activity is an important biomarker for the presence of neurodegenerative diseases,
cerebrovascular alterations, and brain trauma; furthermore, it is a surrogate marker for …

The right rodent for the job: infarct variability between strains and its impact on logistics of experimental animal studies

S Rewell, DW Howells - Neuroprotective Therapy for Stroke and Ischemic …, 2017 - Springer
This chapter will discuss the variability in infarct size after ischaemic stroke in rat models of
stroke, drawing example from our experience with the thread occlusion model. We will …

Investigation into optimizing laser speckle contrast imaging illumination

JS Arkin - 2017 - repositories.lib.utexas.edu
The primary purpose of this work is to optimize the illumination parameters used for laser
speckle imaging and investigate how spatial modulation of the light used for illumination can …