Persistent bacterial infections and persister cells
RA Fisher, B Gollan, S Helaine - Nature Reviews Microbiology, 2017 - nature.com
Many bacteria can infect and persist inside their hosts for long periods of time. This can be
due to immunosuppression of the host, immune evasion by the pathogen and/or ineffective …
due to immunosuppression of the host, immune evasion by the pathogen and/or ineffective …
Pseudomonas aeruginosa biofilm, a programmed bacterial life for fitness
A biofilm is a community of microbes that typically inhabit on surfaces and are encased in an
extracellular matrix. Biofilms display very dissimilar characteristics to their planktonic …
extracellular matrix. Biofilms display very dissimilar characteristics to their planktonic …
Use of oxygen therapies in wound healing: focus on topical and hyperbaric oxygen treatment
F Gottrup, J Dissemond, C Baines… - Journal of wound …, 2017 - magonlinelibrary.com
Among other things wound healing requires restoration of macro-and microcirculation as
essential conditions for healing. 1, 2 One of the most 'immediate'requirements is oxygen …
essential conditions for healing. 1, 2 One of the most 'immediate'requirements is oxygen …
[HTML][HTML] The consequences of being in an infectious biofilm: microenvironmental conditions governing antibiotic tolerance
M Sønderholm, T Bjarnsholt, M Alhede… - International journal of …, 2017 - mdpi.com
The main driver behind biofilm research is the desire to understand the mechanisms
governing the antibiotic tolerance of biofilm-growing bacteria found in chronic bacterial …
governing the antibiotic tolerance of biofilm-growing bacteria found in chronic bacterial …
[HTML][HTML] CRISPR Interference (CRISPRi) Inhibition of luxS Gene Expression in E. coli: An Approach to Inhibit Biofilm
Biofilm is a sessile bacterial accretion embedded in self-producing matrix. It is the root cause
of about 80% microbial infections in human. Among them, E. coli biofilms are most prevalent …
of about 80% microbial infections in human. Among them, E. coli biofilms are most prevalent …
[HTML][HTML] Flow environment and matrix structure interact to determine spatial competition in Pseudomonas aeruginosa biofilms
Bacteria often live in biofilms, which are microbial communities surrounded by a secreted
extracellular matrix. Here, we demonstrate that hydrodynamic flow and matrix organization …
extracellular matrix. Here, we demonstrate that hydrodynamic flow and matrix organization …
Potentiation of tobramycin by silver nanoparticles against Pseudomonas aeruginosa biofilms
MB Habash, MC Goodyear, AJ Park… - Antimicrobial agents …, 2017 - Am Soc Microbiol
Increasing antibiotic resistance among pathogenic bacterial species is a serious public
health problem and has prompted research examining the antibacterial effects of alternative …
health problem and has prompted research examining the antibacterial effects of alternative …
Surfactants and their role in wound cleansing and biofilm management
SL Percival, D Mayer, M Malone… - Journal of wound …, 2017 - magonlinelibrary.com
Surfactants are widely used as detergents, emulsifiers, wetting agents, foaming agents and
dispersants in the cosmetics, hygiene, food and oil industries. Their use in a clinical setting …
dispersants in the cosmetics, hygiene, food and oil industries. Their use in a clinical setting …
Discovery of a Novel Nitric Oxide Binding Protein and Nitric-Oxide-Responsive Signaling Pathway in Pseudomonas aeruginosa
S Hossain, EM Boon - ACS infectious diseases, 2017 - ACS Publications
Nitric oxide (NO) is a radical diatomic gas molecule that, at low concentrations, plays
important signaling roles in both eukaryotes and bacteria. In recent years, it has become …
important signaling roles in both eukaryotes and bacteria. In recent years, it has become …
Cadexomer iodine provides superior efficacy against bacterial wound biofilms in vitro and in vivo
DJ Fitzgerald, PJ Renick, EC Forrest… - Wound repair and …, 2017 - Wiley Online Library
Examination of clinical samples indicates bacterial biofilms are present in the majority of
chronic wounds, and substantial evidence suggests biofilms contribute significantly to …
chronic wounds, and substantial evidence suggests biofilms contribute significantly to …