Evolution of the modified Rankin scale and its use in future stroke trials

JP Broderick, O Adeoye, J Elm - Stroke, 2017 - Am Heart Assoc
2008 Stroke July 2017 mRS that depend, in part, on meeting or not meeting the proportional
odds assumption. 16, 18 After scientific discussion and debate in the field, investigators …

[HTML][HTML] Management of spontaneous intracerebral hemorrhage

R Veltkamp, J Purrucker - Current neurology and neuroscience reports, 2017 - Springer
Abstract Purpose of Review We review the current evidence for medical and surgical
treatments of spontaneous intracerebral hemorrhage (ICH). Recent Findings Therapy with …

Challenges for intraventricular hemorrhage research and emerging therapeutic targets

T Garton, Y Hua, J Xiang, G Xi… - Expert opinion on …, 2017 - Taylor & Francis
Introduction: Intraventricular hemorrhage (IVH) affects both premature infants and adults. In
both demographics, it has high mortality and morbidity. There is no FDA approved therapy …

CSF inflammatory response after intraventricular hemorrhage

MD Fam, HA Zeineddine, JK Eliyas, A Stadnik… - Neurology, 2017 - AAN Enterprises
Objective: To investigate the temporal pattern and relevant associations of CSF inflammatory
measures after intraventricular hemorrhage (IVH). Methods: We analyzed prospectively …

Significance of satellite sign and spot sign in predicting hematoma expansion in spontaneous intracerebral hemorrhage

Z Yu, J Zheng, H Ali, R Guo, M Li, X Wang, L Ma… - Clinical Neurology and …, 2017 - Elsevier
Objectives Hematoma expansion is related to poor outcome in spontaneous intracerebral
hemorrhage (ICH). Recently, a non-enhanced computed tomography (CT) based finding …

Permanent CSF shunting after intraventricular hemorrhage in the CLEAR III trial

SB Murthy, I Awad, S Harnof, F Aldrich, M Harrigan… - Neurology, 2017 - AAN Enterprises
Objective: To study factors associated with permanent CSF diversion and the relationship
between shunting and functional outcomes in spontaneous intraventricular hemorrhage …

Early management of acute cerebrovascular accident

J Manners, A Steinberg, L Shutter - Current opinion in critical care, 2017 - journals.lww.com
Advancing therapeutics in ischemic and hemorrhagic stroke are changing acute care
intervention and broadening potential candidates for what were once thought to be …

[HTML][HTML] Spontaneous intraventricular hemorrhage: when should intraventricular tPA be considered?

PA Abdelmalik, WC Ziai - Seminars in Respiratory and Critical …, 2017 - thieme-connect.com
Spontaneous intracerebral hemorrhage (ICH) is the most common cause of intraventricular
hemorrhage (IVH) in adults. Complicating approximately 40% of ICH cases, IVH adds to the …

Genetic inhibition of receptor interacting protein kinase-1 reduces cell death and improves functional outcome after intracerebral hemorrhage in mice

S Lule, L Wu, LM McAllister, WJ Edmiston III, JY Chung… - Stroke, 2017 - Am Heart Assoc
Background and Purpose—Recent studies using cultured cells and rodent intracerebral
hemorrhage (ICH) models have implicated RIPK1 (receptor interacting protein kinase-1) as …

Local fibrinolytic therapy for intraventricular hemorrhage: a meta-analysis of randomized controlled trials

D Wang, J Liu, C Norton, M Liu, M Selim - World neurosurgery, 2017 - Elsevier
Background The safety and efficacy of intraventricular fibrinolysis (IVF) in patients with
intraventricular hemorrhage (IVH) are unclear. We aimed to determine these issues and to …