Recent developments in radiotherapy

DE Citrin - New England journal of medicine, 2017 - Mass Medical Soc
Recent Developments in Radiotherapy | NEJM Skip to main content NEJM Group Follow Us
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Patient-reported outcomes in cancer care—hearing the patient voice at greater volume

TW LeBlanc, AP Abernethy - Nature reviews Clinical oncology, 2017 - nature.com
Recording of patient-reported outcomes (PROs) enables direct measurement of the
experiences of patients with cancer. In the past decade, the use of PROs has become a …

Immuno-oncology trial endpoints: capturing clinically meaningful activity

V Anagnostou, M Yarchoan, AR Hansen, H Wang… - Clinical Cancer …, 2017 - AACR
Immuno-oncology (IO) has required a shift in the established paradigm of toxicity and
response assessment in clinical research. The design and interpretation of cancer clinical …

Outcomes of immunosuppressive therapy in chronic hypersensitivity pneumonitis

A Adegunsoye, JM Oldham, ERF Pérez… - ERJ Open …, 2017 - Eur Respiratory Soc
In chronic hypersensitivity pneumonitis (CHP), lack of improvement or declining lung
function may prompt use of immunosuppressive therapy. We hypothesised that use of …

Feasibility assessment of patient reporting of symptomatic adverse events in multicenter cancer clinical trials

E Basch, AC Dueck, LJ Rogak, LM Minasian… - JAMA …, 2017 - jamanetwork.com
Importance In cancer clinical trials, symptomatic adverse events (AEs), such as nausea, are
reported by investigators rather than by patients. There is increasing interest to collect …

[HTML][HTML] R-IDEAL: a framework for systematic clinical evaluation of technical innovations in radiation oncology

HM Verkooijen, LGW Kerkmeijer, CD Fuller… - Frontiers in …, 2017 - frontiersin.org
The pace of innovation in radiation oncology is high and the window of opportunity for
evaluation narrow. Financial incentives, industry pressure, and patients' demand for high …

Management of radiation toxicity in head and neck cancers

F Siddiqui, B Movsas - Seminars in Radiation Oncology, 2017 - Elsevier
Head and neck cancers account for approximately 3% of all cancers in the United States
with 62,000 new cases diagnosed annually. The global incidence is approximately 700,000 …

Treatment‐associated toxicities reported by patients with early‐stage invasive breast cancer

CR Friese, JM Harrison, NK Janz, R Jagsi, M Morrow… - Cancer, 2017 - Wiley Online Library
BACKGROUND Patient‐reported toxicities help to appraise the breast cancer treatment
experience. Yet extant data come from clinical trials and health care claims, which may be …

Patient-reported outcome measures (PROMs) in the management of lung cancer: a systematic review

YB Bouazza, I Chiairi, O El Kharbouchi, L De Backer… - Lung cancer, 2017 - Elsevier
Lung cancer is often associated with a poor quality of life, as reflected by patient-reported
outcome measures (PROMs). The aim of this paper is to describe and compare the PROMs …

The natural history of erectile dysfunction after prostatic radiotherapy: a systematic review and meta-analysis

TW Gaither, MA Awad, EC Osterberg… - The journal of sexual …, 2017 - academic.oup.com
Background Erectile dysfunction (ED) after treatment for prostate cancer with radiotherapy
(RT) is well known, and pooled estimates of ED after RT will provide more accurate patient …