[HTML][HTML] The clinical application of microRNAs in infectious disease

RE Drury, D O'Connor, AJ Pollard - Frontiers in immunology, 2017 - frontiersin.org
MicroRNAs (miRNAs) are short single-stranded non-coding RNA sequences that
posttranscriptionally regulate up to 60% of protein encoding genes. Evidence is emerging …

[HTML][HTML] Pulmonary immune responses to Mycobacterium tuberculosis in exposed individuals

C Herzmann, M Ernst, C Lange, S Stenger… - PLoS …, 2017 - journals.plos.org
Background Blood based Interferon-(IFN)-γ release assays (IGRAs) have a poor predictive
value for the development of tuberculosis. This study aimed to investigate the correlation …

[PDF][PDF] The novel immuno-regulatory effects of the Hepatitis C Virus (HCV) protein p7

O Convery - 2017 - tara.tcd.ie
Within HCV-infected hepatocytes, the virus is detected by the PRRs, TLR3 and RIG-I [551].
Following activation, TLR3 recruits the adaptor molecule TRIF [552], while RIG-I recruits …