When plant-pathogenic oomycetes infect their hosts, they employ a large arsenal of effector
proteins to establish a successful infection. Some effector proteins are secreted and are …

N-α-acetyltransferase D (NatD) mediates N-α-terminal acetylation (Nt-acetylation) of histone
H4 known to be involved in cell growth. Here we report that NatD promotes the migratory …

Histone acetyltransferases (HATs) catalyzing N-epsilon-lysine or N-alpha-terminal
acetylation on histone and non-histone substrates are important epigenetic regulators …

Various forms of protein (proteoforms) are generated by genetic variations, alternative
splicing, alternative translation initiation, co-or post-translational modification and …

In eukaryotes, N-terminal acetylation is one of the most common protein modifications
involved in a wide range of biological processes. Most N-acetyltransferase complexes …

The NatB N-terminal acetyltransferase specifically acetylates the N-terminal group of
substrate protein peptides starting with Met-Asp/Glu/Asn/Gln. How NatB recognizes and …

Background Post-translational modification (PTM) of proteins is central to many cellular
processes across all domains of life, but despite decades of study and a wealth of genomic …

Aims Current non-invasive diagnostics for acute myocardial infarction (MI) identify
myocardial necrosis rather than the primary cause and therapeutic target—plaque disruption …

Amino‐terminal acetylation is a ubiquitous protein modification affecting the majority of
eukaryote proteins to regulate stability and function. We describe an optimised recombinant …

The organization of the Golgi apparatus (GA) is tightly regulated. Golgi stack scattering is
observed in cellular processes such as apoptosis and mitosis, and has also been …