Long non-coding RNA Linc-RAM enhances myogenic differentiation by interacting with MyoD

X Yu, Y Zhang, T Li, Z Ma, H Jia, Q Chen… - Nature …, 2017 - nature.com
Long non-coding RNAs (lncRNAs) are important regulators of diverse biological processes.
Here we report on functional identification and characterization of a novel long intergenic …

Ethylene-induced transcriptional and hormonal responses at the onset of sugarcane ripening

CP Cunha, GG Roberto, R Vicentini, CG Lembke… - Scientific Reports, 2017 - nature.com
The effects of ethephon as a sugarcane ripener are attributed to ethylene. However, the role
of this phytohormone at the molecular level is unknown. We performed a transcriptome …

Genome-wide identification and characterization of miRNAome from tomato (Solanum lycopersicum) roots and root-knot nematode (Meloidogyne incognita) during …

P Kaur, N Shukla, G Joshi, C VijayaKumar… - PLoS …, 2017 - journals.plos.org
Root-knot nematodes (RKNs, Meloidogyne spp.) are the most damaging plant parasites
causing severe losses to crop production. The present study reports genome-wide …

Multiple miRNAs jointly regulate the biosynthesis of ecdysteroid in the holometabolous insects, Chilo suppressalis

K He, Y Sun, H Xiao, C Ge, F Li, Z Han - Rna, 2017 - rnajournal.cshlp.org
The accurate rise and fall of active hormones is important for insect development. The
ecdysteroids must be cleared in a timely manner. However, the mechanism of suppressing …

Detecting disease specific pathway substructures through an integrated systems biology approach

S Alaimo, GP Marceca, A Ferro, A Pulvirenti - Non-coding RNA, 2017 - mdpi.com
In the era of network medicine, pathway analysis methods play a central role in the
prediction of phenotype from high throughput experiments. In this paper, we present a …

Neuroplasticity pathways and protein-interaction networks are modulated by vortioxetine in rodents

JA Waller, SH Nygaard, Y Li, KG Du Jardin, JA Tamm… - BMC neuroscience, 2017 - Springer
Background The identification of biomarkers that predict susceptibility to major depressive
disorder and treatment response to antidepressants is a major challenge. Vortioxetine is a …

Natural selection drove metabolic specialization of the chromatophore in Paulinella chromatophora

C Valadez-Cano, R Olivares-Hernández… - BMC Evolutionary …, 2017 - Springer
Background Genome degradation of host-restricted mutualistic endosymbionts has been
attributed to inactivating mutations and genetic drift while genes coding for host-relevant …

SANe: the seed active network for discovering transcriptional regulatory programs of seed development

C Gupta, A Krishnan, A Schneider, C Denbow… - bioRxiv, 2017 - biorxiv.org
Developing seeds undergo coordinated physiological and morphological changes crucial
for development of the embryo, dormancy and germination. The metabolic changes that …

Bioinformatics methods to deduce biological interpretation from proteomics data

K Patel, M Singh, H Gowda - Proteome Bioinformatics, 2017 - Springer
High-throughput proteomics studies generate large amounts of data. Biological
interpretation of these large scale datasets is often challenging. Over the years, several …

[PDF][PDF] Semi-automated framework for the analytical use of gene-centric data with biological ontologies

X He - 2017 - core.ac.uk
Motivation Translational bioinformatics (TBI) has been defined as 'the development and
application of informatics methods that connect molecular entities to clinical entities'[1] …