Understanding memory CD8+ T cells

T Samji, KM Khanna - Immunology letters, 2017 - Elsevier
Memory CD8+ T cells were originally thought to exist as two populations (effector and
central memory). In recent years, a third population called resident memory T cells has been …

IL-15 complexes induce migration of resting memory CD8 T cells into mucosal tissues

RT Sowell, JW Goldufsky, M Rogozinska… - The Journal of …, 2017 - journals.aai.org
IL-15 is an essential cytokine known to promote T cell survival and activate the effector
function of memory phenotype CD8 T cells. Blocking IL-15 signals also significantly impacts …

HVEM imprints memory potential on effector CD8 T cells required for protective mucosal immunity

P Desai, G Abboud, J Stanfield, PG Thomas… - The Journal of …, 2017 - journals.aai.org
Mucosal immunity to reinfection with a highly virulent virus requires the accumulation and
persistence of memory CD8 T cells at the site of primary infection. These cells may derive …

IL-10 distinguishes a unique population of activated, effector-like CD8+ T cells in murine acute liver inflammation

JE Rood, SW Canna, LK Weaver… - Journal of Leucocyte …, 2017 - academic.oup.com
Immune-mediated liver injury is a central feature of hyperinflammatory diseases, such as
hemophagocytic syndromes, yet the immunologic mechanisms underlying those processes …

Activation and exhaustion of antigen-specific CD8+ T cells occur in different splenic compartments during infection with Plasmodium berghei

G Bayarsaikhan, M Miyakoda, K Yamamoto… - Parasitology …, 2017 - Elsevier
The spleen is the major organ in which T cells are primed during infection with malaria
parasites. However, little is known regarding the dynamics of the immune responses and …

Homeostatic memory and virtual memory CD8+ T cells

M Přibíková - 2017 - dspace.cuni.cz
This work sums up current knowledge of so-called homeostatic proliferation-induced
memory CD8+ T cells (HP) and virtual memory CD8+ T cells. These populations do not …