Stereoselective Synthesis of Tetrasubstituted Alkenes via a Cp*CoIII‐Catalyzed C−H Alkenylation/Directing Group Migration Sequence
H Ikemoto, R Tanaka, K Sakata, M Kanai… - Angewandte Chemie …, 2017 - Wiley Online Library
A highly atom economical and stereoselective synthesis of tetrasubstituted α, β‐unsaturated
amides was achieved by a Cp* CoIII‐catalyzed C− H alkenylation/directing group migration …
amides was achieved by a Cp* CoIII‐catalyzed C− H alkenylation/directing group migration …
Highly stereoselective synthesis of tetrasubstituted acyclic all-carbon olefins via enol tosylation and Suzuki–Miyaura coupling
A highly stereocontrolled synthesis of tetrasubstituted acyclic all-carbon olefins has been
developed via a stereoselective enolization and tosylate formation, followed by a palladium …
developed via a stereoselective enolization and tosylate formation, followed by a palladium …
Design, synthesis, biological evaluation and molecular docking studies of novel 3-aryl-4-anilino-2H-chromen-2-one derivatives targeting ERα as anti-breast cancer …
The estrogen receptor (ER) has played an important role in breast cancer development and
progression and is a central target for anticancer drug discovery. In order to develop novel …
progression and is a central target for anticancer drug discovery. In order to develop novel …
Photoredox-Catalyzed C–H Arylation of Internal Alkenes to Tetrasubstituted Alkenes: Synthesis of Tamoxifen
Q Wang, X Yang, P Wu, Z Yu - Organic letters, 2017 - ACS Publications
Visible-light-induced direct C–H arylation of S, S-functionalized internal alkenes, that is, α-
oxo ketene dithioacetals and analogues, has been efficiently realized with aryldiazonium …
oxo ketene dithioacetals and analogues, has been efficiently realized with aryldiazonium …
Lithium Hexamethyldisilazide-Mediated Enolization of Highly Substituted Aryl Ketones: Structural and Mechanistic Basis of the E/Z Selectivities
Enolizations of highly substituted acyclic ketones used in the syntheses of tetrasubstituted
olefin-based anticancer agents are described. Lithium hexamethyldisilazide (LiHMDS) …
olefin-based anticancer agents are described. Lithium hexamethyldisilazide (LiHMDS) …
Cesium-catalyzed highly regioselective synthesis of (Z)-vinylic selenosulfides via thioselenation of alkynes with unsymmetrical diorganoyl dichalcogenides
L Peng, R Li, Z Tang, J Chen, R Yi, X Xu - Tetrahedron, 2017 - Elsevier
A novel one-pot approach for the synthesis of (Z)-vinylic selenosulfides is demonstrated
through the thioselenation of a wide range of alkynes with unsymmetrical diorganoyl …
through the thioselenation of a wide range of alkynes with unsymmetrical diorganoyl …