Components of the Wnt signaling cascade represent novel targets for pharmacological
intervention in cardiometabolic disease. Conversely, strategies targeting the Wnt signaling …

Many of the clinical trials developed in the last decade to reduce atherosclerosis and
cardiovascular diseases have been futile or have failed possibly because of a poor …

Several clinical studies reported that Dickkopf1 (DKK1) plasma levels are correlated with
atherosclerosis. However, the impact of DKK1 on the formation and vulnerability of …

Background: Dickkopf-related protein 3 (DKK3) is a secreted protein that is involved in the
regulation of cardiac remodeling and vascular smooth muscle cell differentiation, but little is …

Introduction Mounting evidence indicates that a disturbed Wnt–β-catenin signaling may be
involved in the pathogenesis of chronic kidney disease-mineral and bone and mineral …

Abstract Dikkoppf-1 (DKK1) is an antagonist of the canonical Wnt signaling pathway. The
importance of DKK1 as a diagnostic and therapeutic agent in a wide range of diseases …

Background & aims Hepatitis B virus (HBV)-related hepatocellular carcinoma (HCC) is
prevalent worldwide. Despite its limitations, serum alpha-fetoprotein (AFP) remains the most …

Abstract Excessive Dickkopf-1 (Dkk-1) plays a vital role in secondary brain injury following
ischemic stroke and psychotic disease. However, it is unclear whether an increased …

Introduction. Cardiovascular (CV) diseases are a major cause of death in rheumatoid
arthritis (RA) patients. Novel biomarkers [B‐type natriuretic peptide (BNP); osteoprotegerin …

Context: There is great interest in the biology of vascular calcification. Wnt/β-catenin
signaling is an important mediator of mineralization and may play a role in vascular …