Targeting latency-associated peptide promotes antitumor immunity

G Gabriely, AP da Cunha, RM Rezende… - Science …, 2017 - science.org
Regulatory T cells (Tregs) promote cancer by suppressing antitumor immune responses. We
found that anti-LAP antibody, which targets the latency-associated peptide …

Encapsulation of an EP67-conjugated CTL peptide vaccine in nanoscale biodegradable particles increases the efficacy of respiratory immunization and affects the …

BVK Karuturi, SB Tallapaka, P Yeapuri… - Molecular …, 2017 - ACS Publications
The diameter of biodegradable particles used to coencapsulate immunostimulants and
subunit vaccines affects the magnitude of memory CD8+ T cells generated by systemic …

Effector functions of memory CTLs can be affected by signals received during reactivation

Y Lv, E Mattson, A Bhadurihauck, K Garcia, L Li… - Immunologic …, 2017 - Springer
Memory cytotoxic T lymphocytes (CTLs) are able to provide protections to the host against
repeated insults from intracellular pathogens. However, it has not been completely …