Inhibition of toll-like receptor signaling as a promising therapy for inflammatory diseases: a journey from molecular to nano therapeutics
W Gao, Y Xiong, Q Li, H Yang - Frontiers in physiology, 2017 - frontiersin.org
The recognition of invading pathogens and endogenous molecules from damaged tissues
by toll-like receptors (TLRs) triggers protective self-defense mechanisms. However …
by toll-like receptors (TLRs) triggers protective self-defense mechanisms. However …
Cell‐to‐cell communication: microRNAs as hormones
R Bayraktar, K Van Roosbroeck… - Molecular oncology, 2017 - Wiley Online Library
Mammalian cells can release different types of extracellular vesicles (EVs), including
exosomes, microvesicles, and apoptotic bodies. Accumulating evidence suggests that EVs …
exosomes, microvesicles, and apoptotic bodies. Accumulating evidence suggests that EVs …
Rheumatoid arthritis: recent advances on its etiology, role of cytokines and pharmacotherapy
J Alam, I Jantan, SNA Bukhari - Biomedicine & pharmacotherapy, 2017 - Elsevier
An autoimmune disease is defined as a clinical syndrome resulted from an instigation of
both T cell and B cell or individually, in the absence of any present infection or any sort of …
both T cell and B cell or individually, in the absence of any present infection or any sort of …
Cross talk: the microbiota and neurodevelopmental disorders
Humans evolved within a microbial ecosystem resulting in an interlinked physiology. The gut
microbiota can signal to the brain via the immune system, the vagus nerve or other host …
microbiota can signal to the brain via the immune system, the vagus nerve or other host …
[HTML][HTML] Biological activities of extracellular vesicles and their cargos from bovine and human milk in humans and implications for infants
Extracellular vesicles (EVs) in milk harbor a variety of compounds, including lipids, proteins,
noncoding RNAs, and mRNAs. Among the various classes of EVs, exosomes are of …
noncoding RNAs, and mRNAs. Among the various classes of EVs, exosomes are of …
Tumor induces muscle wasting in mice through releasing extracellular Hsp70 and Hsp90
Cachexia, characterized by muscle wasting, is a major contributor to cancer-related
mortality. However, the key cachexins that mediate cancer-induced muscle wasting remain …
mortality. However, the key cachexins that mediate cancer-induced muscle wasting remain …
Pathogen recognition and Toll-like receptor targeted therapeutics in innate immune cells
S Tartey, O Takeuchi - International reviews of immunology, 2017 - Taylor & Francis
The innate immune system deploys a variety of pattern-recognition receptors (PRRs) which
include Toll-like receptors (TLRs), RIG-I-like receptors, NOD-like receptors, and C-type lectin …
include Toll-like receptors (TLRs), RIG-I-like receptors, NOD-like receptors, and C-type lectin …
Danger-associated molecular patterns in Alzheimer's disease
C Venegas, MT Heneka - Journal of Leucocyte Biology, 2017 - academic.oup.com
Pathogen-associated molecular patterns (PAMPs) and endogenous “danger” signals,
known as danger-associated molecular patterns (DAMPs), released from cells alert the …
known as danger-associated molecular patterns (DAMPs), released from cells alert the …
The toll for trafficking: toll-like receptor 7 delivery to the endosome
Toll-like receptor (TLR)-7 is an endosomal innate immune sensor capable of detecting
single-stranded ribonucleic acid. TLR7-mediated induction of type I interferon and other …
single-stranded ribonucleic acid. TLR7-mediated induction of type I interferon and other …
The role of the immune system beyond the fight against infection
S Sattler - The immunology of cardiovascular homeostasis and …, 2017 - Springer
The immune system was identified as a protective factor during infectious diseases over a
century ago. Current definitions and textbook information are still largely influenced by these …
century ago. Current definitions and textbook information are still largely influenced by these …