Glioblastoma multiforme (GBM) are mortifying brain tumours that contain a subpopulation of
tumour cells with stem-like properties, termed glioblastoma stem-like cells (GSCs). GSCs …

Post-transcriptional regulation of messenger RNA (mRNA) metabolism and subcellular
localization is of the utmost importance both during development and in cell differentiation …

Glioma stem cells (GSCs) play an important role in glioblastoma prognosis. Exosomes (EXs)
mediate cell communication by delivering microRNAs (miRs). Glioblastoma has a high level …

Tumor endothelial cells regulate several aspects of tumor biology, from delivering oxygen
and nutrients to shaping the immune response against a tumor and providing a barrier …

Naturally occurring extracellular vesicles (EVs) play essential roles in intracellular
communication and delivery of bioactive molecules. Therefore it has been suggested that …

Background: Glioblastoma multiforme (GBM) is the most aggressive and deadly primary
brain cancer that arises from astrocytes and classified as grade IV. Recently, exosomes …

Discovered decades ago, extracellular vesicles (EVs) emerge as dedicated organelles, able
to deliver protected, specific cellular cues throughout the organism. While virtually every cell …

Malignant glioma cells invade the surrounding brain parenchyma, by migrating along the
blood vessels, thus promoting cancer growth. The biological bases of these activities are …

Resumen Facultad de Medicina y Odontología Departamento de Medicina Programa de
Doctorado 3042 Medicina Tesis Doctoral Marcadores de angiogénesis, inflamación y …

Recent studies have also highlighted the key role of Met in gliomagenesis and the role that
this oncogene has with EGFR in promoting the malignant phenotype. Met is transactivated …