Angiogenesis is defined as the physiological process by which new blood vessels develop
from pre-existing vessels; either by sprouting or intussusception. Inhibition of angiogenesis …

Pulmonary arterial hypertension (PAH) has been frequently compared with a type of
malignant disease and has an incredible number of pathogenic mechanisms similar to …

Osteosarcoma (OS) is a highly aggressive pediatric cancer, characterized by frequent lung
metastasis and pathologic bone destruction. Vascular endothelial growth factor A (VEGFA) …

Osteosarcomas (OS), especially those with metastatic or unresectable disease, have limited
treatment options. The greatest advancement in treatments occurred in the 1980s when …

Therapeutic outcome for the treatment of glioma was often limited due to drug resistance
and low permeability of drug across the multiple physiological barriers, including the blood …

Among the various advantages of aptamers over antibodies, remarkable is their ability to
tolerate a large number of chemical modifications within their backbone or at the termini …

Serine/arginine-protein kinase 1 (SRPK1) regulates alternative splicing of VEGF-A to pro-
angiogenic isoforms and SRPK1 inhibition can restore the balance of pro/antiangiogenic …

Molecular imaging continues to influence every aspect of cancer care including detection,
diagnosis, staging and therapy response assessment. Recent advances in the …

Novel series of phthalazine derivatives 6–11 were designed, synthesized, and evaluated for
their anticancer activity against two human tumor cell lines, HCT‐116 human colon …

Tumor-targeted delivery of anticancer drugs using dendrimers has been recognized as a
promising strategy to increase efficiency and reduce adverse effects of chemotherapy …