Non-thermal plasma induces immunogenic cell death in vivo in murine CT26 colorectal tumors

AG Lin, B Xiang, DJ Merlino, TR Baybutt, J Sahu… - …, 2018 - Taylor & Francis
Immunogenic cell death is characterized by the emission of danger signals that facilitate
activation of an adaptive immune response against dead-cell antigens. In the case of cancer …

A monomethyl auristatin E-conjugated antibody to guanylyl cyclase C is cytotoxic to target-expressing cells in vitro and in vivo

M Gallery, J Zhang, DP Bradley, P Brauer, D Cvet… - PLoS …, 2018 - journals.plos.org
Guanylyl cyclase C (GCC) is a cell-surface protein that is expressed by normal intestinal
epithelial cells, more than 95% of metastatic colorectal cancers (mCRC), and the majority of …

Optimisation de la réponse immune après traitement locorégional de tumeurs colorectales murines

KLA Lemdani - 2018 - theses.hal.science
Les métastases hépatiques compliquent l'évolution de 50% des cancers colorectaux (CCR).
Plus de la moitié des patients présentent une récidive à distance avec métastases occultes …