Update on multiple endocrine neoplasia type 2: focus on medullary thyroid carcinoma

F Raue, K Frank-Raue - Journal of the Endocrine Society, 2018 - academic.oup.com
Multiple endocrine neoplasia type 2 (MEN2) is an autosomal dominant hereditary cancer
syndrome caused by missense gain-of-function mutations in the RET proto-oncogene on …

An improved deep learning approach for detection of thyroid papillary cancer in ultrasound images

H Li, J Weng, Y Shi, W Gu, Y Mao, Y Wang, W Liu… - Scientific reports, 2018 - nature.com
Unlike daily routine images, ultrasound images are usually monochrome and low-resolution.
In ultrasound images, the cancer regions are usually blurred, vague margin and irregular in …

Management of treatment-related toxicities in advanced medullary thyroid cancer

MS Brose, KC Bible, LQM Chow, J Gilbert… - Cancer treatment …, 2018 - Elsevier
Progress in the treatment of advanced medullary thyroid cancer (MTC) has resulted from the
approval of 2 drugs within the past 5 years, vandetanib and cabozantinib. These multikinase …

Circulating miR-375 as a novel prognostic marker for metastatic medullary thyroid cancer patients

P Romeo, C Colombo, R Granata… - Endocrine-related …, 2018 - erc.bioscientifica.com
This study aimed to identify circulating miRNAs as novel non-invasive biomarkers for
prognosis and vandetanib response in advanced medullary thyroid cancer (MTC) patients …

LncRNA GAS8-AS1 inhibits cell proliferation through ATG5-mediated autophagy in papillary thyroid cancer

Y Qin, W Sun, H Zhang, P Zhang, Z Wang, W Dong… - Endocrine, 2018 - Springer
Purpose The long non-coding RNA GAS8 antisense RNA 1 (lncRNA GAS8-AS1) is a tumor
suppressor in papillary thyroid cancer (PTC), but the mechanisms underlying how GAS8 …

Static prognostic factors and appropriate surgical designs for patients with medullary thyroid carcinoma: the second report from a single‐institution study in Japan

Y Ito, A Miyauchi, M Kihara… - World Journal of …, 2018 - Wiley Online Library
Background Medullary thyroid carcinoma (MTC) originates from calcitonin‐producing cells
of the thyroid. In 2009, we published our first report on the biological characteristics and …

Incidence and prevalence of sporadic and hereditary MTC in Denmark 1960–2014: a nationwide study

JS Mathiesen, JP Kroustrup… - Endocrine …, 2018 - ec.bioscientifica.com
Recent studies have shown a significant increase in the temporal trend of medullary thyroid
carcinoma (MTC) incidence. However, it remains unknown to which extent sporadic …

Survival in patients with medullary thyroid cancer after less than the recommended initial operation

RW Randle, MF Bates, DF Schneider… - Journal of surgical …, 2018 - Wiley Online Library
Background and Objectives We aimed to evaluate the disease specific‐survival (DSS) of
patients with Medullary Thyroid Cancer (MTC) confined to the central neck based on the …

Temporal trends in the presentation, treatment, and outcome of medullary thyroid carcinoma: an Israeli multicenter study

D Hirsch, O Twito, S Levy, G Bachar, E Robenshtok… - Thyroid, 2018 - liebertpub.com
Background: The widespread use of neck sonography in recent years has led to a dramatic
increase in the detection of thyroid cancer, accompanied by changes in the clinicopathologic …

No calcitonin change in a person taking dulaglutide diagnosed with pre‐existing medullary thyroid cancer

SI Sherman, RT Kloos, RM Tuttle… - Diabetic …, 2018 - Wiley Online Library
Background Glucagon‐like peptide‐1 receptor agonists, such as dulaglutide, exenatide and
liraglutide, are approved to treat Type 2 diabetes mellitus. Although these drugs provide …