Protein structural biology came a long way since the determination of the first three-
dimensional structure of myoglobin about six decades ago. Across this period, X-ray …

Chemical shifts are highly sensitive probes harnessed by NMR spectroscopists and
structural biologists as conformational parameters to characterize a range of biological …

Exosomal miRNA transfer is a mechanism for cell–cell communication that is important in
the immune response, in the functioning of the nervous system and in cancer …

The molecular chaperone Hsp90 is critical for the maintenance of cellular homeostasis and
represents a promising drug target. Despite increasing knowledge on the structure of Hsp90 …

Background The WRKY transcription factors are a class of DNA-binding proteins involved in
diverse plant processes play critical roles in response to abiotic and biotic stresses. Genome …

In this present study, a gene (ent-B) encoding the bacteriocin enterocin-B was cloned,
overexpressed and purified from Enterococcus faecium por1. The molecular weight of the …

We present a general strategy for determining the cholesterol-binding site of eukaryotic
membrane proteins in native-like lipid membranes by NMR spectroscopy. The strategy …

Motivation Protein–peptide interactions are one of the most important biological interactions
and play crucial role in many diseases including cancer. Therefore, knowledge of these …

Respiratory syncytial virus (RSV) RNA synthesis occurs in cytoplasmic inclusion bodies (IBs)
in which all the components of the viral RNA polymerase are concentrated. In this work, we …

Computational protein docking is a powerful strategy to predict structures of protein-protein
interactions and provides crucial insights for the functional characterization of …