[HTML][HTML] Neurobiology and consequences of social isolation stress in animal model—A comprehensive review

F Mumtaz, MI Khan, M Zubair, AR Dehpour - Biomedicine & …, 2018 - Elsevier
The brain is a vital organ, susceptible to alterations under genetic influences and
environmental experiences. Social isolation (SI) acts as a stressor which results in …

Oxytocin and social relationships: from attachment to bond disruption

OJ Bosch, LJ Young - Behavioral pharmacology of neuropeptides …, 2018 - Springer
Social relationships throughout life are vital for well-being and physical and mental health. A
significant amount of research in animal models as well as in humans suggests that oxytocin …

Loneliness in the modern age: An evolutionary theory of loneliness (ETL)

JT Cacioppo, S Cacioppo - Advances in experimental social psychology, 2018 - Elsevier
Abstract We describe the Cacioppo Evolutionary Theory of Loneliness (ETL) and its
manifestations in contemporary society. The early conceptualizations of loneliness were as …

Facial expression and oxytocin as possible markers of positive emotions in horses

L Lansade, R Nowak, AL Lainé, C Leterrier… - Scientific reports, 2018 - nature.com
Behavioural and physiological markers of discrete positive emotions remain little
investigated in animals. To characterise new markers in horses, we used tactile stimulations …

Relevance of rodent models of depression in clinical practice: can we overcome the obstacles in translational neuropsychiatry?

J Söderlund, M Lindskog - International Journal of …, 2018 - academic.oup.com
The diagnosis of a mental disorder generally depends on clinical observations and
phenomenological symptoms reported by the patient. The definition of a given diagnosis is …

Social support rescues acute stress-induced cognitive impairments by modulating ERK1/2 phosphorylation in adolescent mice

JW Kim, MJ Ko, EL Gonzales, RJ Kang, DG Kim… - Scientific reports, 2018 - nature.com
Social support can relieve stress-induced behavioural outcomes, although its underlying
molecular mechanisms are not fully understood. Here, we evaluated whether social …

Anxiety-like behavior and neuropeptide receptor expression in male and female prairie voles: the effects of stress and social buffering

M Donovan, Y Liu, Z Wang - Behavioural brain research, 2018 - Elsevier
Strong social support can negate negative health outcomes–an effect defined as 'social
buffering'. In the present study, using the socially monogamous prairie vole (Microtus …

Stereological analysis of microglia in aged male and female fischer 344 rats in socially relevant brain regions

AE Perkins, MK Piazza, T Deak - Neuroscience, 2018 - Elsevier
Aging is associated with a substantial decline in the expression of social behavior as well as
increased neuroinflammation. Since immune activation and subsequent increased …

The impact of stress on social behavior in adult zebrafish (Danio rerio)

SM Saszik, CM Smith - Behavioural pharmacology, 2018 - journals.lww.com
Stress has adverse effects on social behavior that is mediated by dopamine circuits in the
midbrain. The purpose of this research is to examine the effect of chronic stress and …

Oxytocin and human evolution

C Sue Carter - Behavioral Pharmacology of Neuropeptides: Oxytocin, 2018 - Springer
A small, but powerful neuropeptide, oxytocin coordinates processes that are central to both
human reproduction and human evolution. Also embedded in the evolution of the human …