Successful reprogramming of cellular protein production through mRNA delivered by functionalized lipid nanoparticles
M Yanez Arteta, T Kjellman… - Proceedings of the …, 2018 - National Acad Sciences
The development of safe and efficacious gene vectors has limited greatly the potential for
therapeutic treatments based on messenger RNA (mRNA). Lipid nanoparticles (LNPs) …
therapeutic treatments based on messenger RNA (mRNA). Lipid nanoparticles (LNPs) …
[图书][B] Surface and interfacial forces
HJ Butt, M Kappl - 2018 - books.google.com
A general introduction to surface and interfacial forces, perfectly combining theoretical
concepts, experimental techniques and practical applications. In this completely updated …
concepts, experimental techniques and practical applications. In this completely updated …
Transferable MARTINI model of poly (ethylene oxide)
F Grunewald, G Rossi, AH De Vries… - The journal of …, 2018 - ACS Publications
Motivated by the deficiencies of the previous MARTINI models of poly (ethylene
oxide)(PEO), we present a new model featuring a high degree of transferability. The model …
oxide)(PEO), we present a new model featuring a high degree of transferability. The model …
PEG-benzaldehyde-hydrazone-lipid based PEG-sheddable pH-sensitive liposomes: abilities for endosomal escape and long circulation
M Kanamala, BD Palmer, H Ghandehari… - Pharmaceutical …, 2018 - Springer
Purpose To fabricate an acid-cleavable PEG polymer for the development of PEG-cleavable
pH-sensitive liposomes (CL-pPSL), and to investigate their ability for endosomal escape and …
pH-sensitive liposomes (CL-pPSL), and to investigate their ability for endosomal escape and …
Out-of-the-groove transport of lipids by TMEM16 and GPCR scramblases
Phospholipid scramblases externalize phosphatidylserine to facilitate numerous
physiological processes. Several members of the structurally unrelated TMEM16 and G …
physiological processes. Several members of the structurally unrelated TMEM16 and G …
[HTML][HTML] Surface-grafted polyethylene glycol conformation impacts the transport of PEG-functionalized liposomes through a tumour extracellular matrix model
The effect of surface PEGylation on nanoparticle transport through an extracellular matrix
(ECM) is an important determinant for tumor targeting success. Fluorescent stealth …
(ECM) is an important determinant for tumor targeting success. Fluorescent stealth …
Morphology and physical properties of hydrophilic-polymer-modified lipids in supported lipid bilayers
Y Kakimoto, Y Tachihara, Y Okamoto, K Miyazawa… - Langmuir, 2018 - ACS Publications
Lipid molecules such as glycolipids that are modified with hydrophilic biopolymers
participate in the biochemical reactions occurring on cell membranes. Their functions and …
participate in the biochemical reactions occurring on cell membranes. Their functions and …
Effects of 1-hexanol on C 12 E 10 micelles: a molecular simulations and light scattering study
S Vierros, M Sammalkorpi - Physical Chemistry Chemical Physics, 2018 - pubs.rsc.org
The micelles of the non-ionic C12E10 surfactant and 1-hexanol as an aqueous solution
additives are studied toward the purpose of understanding the role of alcohol additives in …
additives are studied toward the purpose of understanding the role of alcohol additives in …
Preserving the inflated structure of lyophilized sporopollenin exine capsules with polyethylene glycol osmolyte
MK Corliss, CK Bok, J Gillissen, MG Potroz… - Journal of industrial and …, 2018 - Elsevier
Extracted from natural pollen grains, sporopollenin exine capsules (SECs) are robust,
chemically inert biopolymer shells that posess highly uniform size and shape characteristics …
chemically inert biopolymer shells that posess highly uniform size and shape characteristics …
[HTML][HTML] Archaeal tetraether lipid coatings—A strategy for the development of membrane analog spacer systems for the site-specific functionalization of medical …
K Liefeith, M Frant, U Müller, P Stenstad, H Johnsen… - …, 2018 - pubs.aip.org
The primary goal of our investigation was the development of a versatile immobilization
matrix based on archaeal tetraether lipids that meets the most important prerequisites to …
matrix based on archaeal tetraether lipids that meets the most important prerequisites to …