Fluorescence lifetime is not only associated with the molecular structure of fluorophores, but
also strongly depends on the environment around them, which allows fluorescence lifetime …

Abstract While NAD (P) H fluorescence lifetime imaging (FLIM) can detect changes in flux
through the TCA cycle and electron transport chain (ETC), it remains unclear whether NAD …

During photodynamic therapy (PDT), disruption of cell respiration and metabolic changes
could be one of the first events. Photophysical characteristics of the photosensitizer (PS) and …

Investigating cerebral metabolism in vivo at a microscopic level is essential for
understanding brain function and its pathological alterations. The intricate signaling and …

Fluorescence lifetime imaging (FLIM) is aiming at the measurement of molecular parameters
in the local environment of the fluorophores. It exploits the fact that the fluorescence decay …

Correlated imaging of phosphorescence and fluorescence lifetime parameters of metabolic
markers is a challenge for direct investigating mechanisms related to cell metabolism and …

Tässä työssä selvitetään Tampereen teknisen yliopiston kemian ja biotekniikan laitoksen
tutkimusryhmälle fluoresenssin elinaika mikroskopiaan (FLIM) soveltuvia merkkiaineita …

In the last two decades, we have seen a transition of microbiological studies from the
population to the single-cell level due to the awareness of heterogeneity in clonal …