Oxidative stress in epilepsy

U Geronzi, F Lotti, S Grosso - Expert Review of Neurotherapeutics, 2018 - Taylor & Francis
Introduction: The brain is particularly susceptible to oxidative stress being the most
aerobically active organ in the body due to its high metabolic demands. There is evidence …

Gastrodin suppresses pentylenetetrazole-induced seizures progression by modulating oxidative stress in zebrafish

M Jin, Q He, S Zhang, Y Cui, L Han, K Liu - Neurochemical research, 2018 - Springer
Pentylenetetrazole (PTZ)-induced seizures in Zebrafish models are now widely accepted for
investigating human disease epilepsy. In epilepsy, the generation of oxidative stress …

[HTML][HTML] Thymelaea lythroides extract attenuates microglial activation and depressive-like behavior in LPS-induced inflammation in adult male rats

I Berkiks, S Boulbaroud, LM Garcia-Segura… - Biomedicine & …, 2018 - Elsevier
Thymelaea lythroides extract is widely used as a traditional folk medicine in Morocco,
especially for the treatment of diabetes, rheumatism and Inflammatory disease. The aim of …

New prospects of mesenchymal stem cells for ameliorating temporal lobe epilepsy

NA Salem, M El-Shamarka, Y Khadrawy… - …, 2018 - Springer
Temporal lobe epilepsy (TLE) is present in 30% of epileptic patients and does not respond
to conventional treatments. Bone marrow derived mesenchymal stem cells (BMSCs) induce …

[HTML][HTML] Amelioration of neurodegeneration and cognitive impairment by Lemon oil in experimental model of Stressed mice

N Falls, D Singh, F Anwar, A Verma, V Kumar - Biomedicine & …, 2018 - Elsevier
Abstract Citrous lemon (Rutaceae) an Indian folk medicine has been used for the treatment
of various pathological diseases viz., diabetes, cardiovascular, inflammation, hepatobiliary …

Anticonvulsant effect of argan oil on pilocarpine model induced status epilepticus in wistar rats

Y Bahbiti, H Ammouri, I Berkiks, AE Hessni… - Nutritional …, 2018 - Taylor & Francis
Argan oil (AO) is rich in oleic and linoleic acids, polyphenols, sterols, and tocopherols. This
composition gives it numerous beneficial pharmacological effects such as hypolipemiant …

Neuroprotective effect of curcumin nanoparticles against rat model of status epilepticus induced by pilocarpine

YA Khadrawy, HG Sawie, EN Hosny - Journal of Complementary and …, 2018 - degruyter.com
Background The present study aims to investigate the neuroprotective effect of curcumin
nanoparticles (Cur-NP) on the rat model of status epilepticus (SE) induced by pilocarpine …

[HTML][HTML] Pilocarpine/ascorbic acid interaction in the immature brain: electrophysiological and oxidative effects in well-nourished and malnourished rats

RF Mendes-da-Silva, E da Silva Francisco… - Brain research …, 2018 - Elsevier
Ascorbic acid (AA) administration has been associated with neuroprotection against
oxidative stress, although at high doses it can facilitate oxidation and acts like a …

Effects of Azadirachta indica leaf aqeous extract on the antioxidant enzymes in paracetamol-induced hepatotoxicity in Wistar rats

EI Nwobodo, DC Nwosu, SO Ogbodo… - International journal of …, 2018 - ajol.info
Azadirachta indica, reported to be antioxidative, is hepatoprotective. This study evaluates
the effect of A. indica leaf aqueous extract on antioxidant enzymes (glutathione peroxidase …

[HTML][HTML] Long-term monotherapy treatment with vitamin E reduces oxidative stress, but not seizure frequency in rats submitted to the pilocarpine model of epilepsy

AP Pansani, RM Cysneiros, DB Colugnati, L Janjoppi… - Epilepsy & Behavior, 2018 - Elsevier
The imbalance between antioxidant system and reactive oxygen species (ROS) generation
is related to epileptogenesis, neuronal death, and seizure frequency. Treatment with vitamin …